Tetrahedron p. 7119 - 7126 (1997)
Update date:2022-07-29
Topics:
Hoffman, Robert V.
Tao, Junhua
An exceedingly simple, general, and stereoselective method for the preparation of ketomethylene dipeptide isosteres (5-(carbobenzyloxyamino)-2-alkyl-γ-ketoesers) from Cbz-protected amino acids and scalemic-2-triflyloxy esters has been developed. The method is short (three steps), efficient, and highly diastereoselective and enantioselective.
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Doi:10.1021/ja513027s
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(1999)Doi:10.1016/S0960-894X(97)00318-1
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(1997)
