191786-64-8Relevant articles and documents
Synthesis and properties of 2'-O-methylribonucleotide methylphosphonate containing chimeric oligonucleotides
Kandimalla,Temsamani,Agrawal
, p. 1031 - 1035 (1995)
2'-O-methylribonucleoside methylphosphonamidites are synthesized and incorporated into oligonucleotides to obtain chimeric antisense oligonucleotides. The resulting oligonucleotide binds to their target RNA/DNA sequences efficiently and stable in a medium containing bovine serum.