19182-95-7

Upstream product

• 5441-16-7 1-(allyloxy)-2,4-dichlorobenzene 
• 119-36-8 methyl salicylate 
• 7606-87-3 methyl 3,5-dichlorosalicylate 
• 500310-54-3 2-allyloxy-3,5-dichloro-benzoic acid 

Downstream Products

• 53890-01-0 (E/Z)-2,4-dichloro-6-(prop-1-enyl)phenol 
• 89197-64-8 1-(2-hydroxy-3,5-dichlorophenyl)-2,3-epoxypropane 
• 33357-14-1 2-acetoxy-1,5-dichloro-3-(2,3-dibromo-propyl)-benzene 

Relevant academic research and scientific papers

UDCaT-5: A novel and efficient solid superacid catalyst for Claisen rearrangement of substituted allyl phenyl ethers

The Claisen rearrangement of allyl phenyl ethers is a fundamental reaction in organic synthesis with a variety of applications in perfumes, flavors, pharmaceuticals, agrochemicals, polymers, fine chemicals, and intermediate industries. The development of environmentally benign processes using solid acid catalysts is becoming an area of growing interest. It was accomplished in an efficient, economical, environmentally friendly manner and is 100% selective toward alllyl phenols by employing UDCaT-5 as solid acid catalyst. Copyright Taylor & Francis Group, LLC.

α-Adrenoreceptor Reagents. 2. Effects of Modification of the 1,4-Benzodioxan Ring System on α-Adrenoreceptor Activity

Modification of the 1,4-benzodioxan ring present in RX 781094 (1) has not previously been considered.This paper describes a number of analogues of this ring system, including compounds in which one of the oxygen atoms has been replaced by a methylene group and also those in which the ring size has been changed to give, for example, furan and thiophene derivatives.The dihydroxybenzofuranylimidazoline compound 7 is the only analogue possesing presynaptic antagonist potency and selectivity comparable to that of 1.In view of this result, a number of derivatives was prepared to determine the structure-activity relationships within this series.Many derivatives, as well as the parent compound 7, were found to possess presynaptic α2-adrenoreceptor antagonist and postsynaptic α1-adrenoreceptor partial agonist properties.Two of the selective presynaptic antagonists,13 and 14, possess greater potency and selectivity than that possessed by 1.The 5-chloro derivative 25 is twice as potent as 1 after oral administration but only about half as potent when given intravenously.