191847-82-2Relevant academic research and scientific papers
BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS
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Page 59, (2008/06/13)
Compounds of formula (I) are useful in the treatment of vanilloid-receptor-meditated diseases, such as inflammatory or neuropathic pain and diseases involving sensory nerve function such as asthma, rheumatoid arthritis, osteoarthritis, inflammatory bowel disorders, urinary incontinence, migraine and psoriasis.
O-Nitroaniline derivatives. Part 14. Cyclisations leading to benzimidazole N-oxides, N-hydroxybenzimidazolones and N-hydroxyquinoxaline-2,3-diones: A mechanistic borderline
Collins Cafiero, Pamela A.,French, Colin S.,McFarlane, Michael D.,Mackie, Raymond K.,Smith, David M.
, p. 1375 - 1384 (2007/10/03)
The base-induced cyclisations of N-(o-nitrophenyl)glycine derivatives (nitriles 9 or esters 13) bearing additional substituents at the other ortho-position are anomalous, resembling those involving N-(o-nitrophenyl)sarcosine analogues. The nitriles are co
