191849-93-1

Usage

Uses

Used in Pharmaceutical Synthesis:
3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be further chemically modified due to the presence of the hydroxy and amino groups.
Used in Drug Development:
In the pharmaceutical industry, 3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid is used as a precursor compound for developing new drugs, leveraging its structural features to target specific biological pathways or receptors.
Used in Chiral Chemistry:
3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid is utilized in chiral chemistry to explore the different properties and potential applications of its R and S enantiomers, which may exhibit distinct biological activities.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid serves as a research tool to investigate the structure-activity relationships of drug candidates and optimize their pharmacological properties.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 209173-80-8 2(RS)-hydroxy-3(S)-amino-4-phenylbutanoic acid 
• 1201292-56-9 (R,S)-α-hydroxy, (S)-β-amino, 4-phenylbutyric acid hydrochloride 
• 186393-18-0 ((S)-1-benzyl-2-cyano-2-hydroxy-ethyl)-carbamic acid tert-butyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 3182-95-4 L-Phenylalaninol 
• 301544-38-7 tert-butyl ((2S)-4-(tert-butylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)carbamate 
• 87694-53-9 Boc-Phe-OH N,O-dimethyl hydroxamate 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 72155-45-4 Boc-L-phenylalaninal 

Downstream Products

• 820993-44-0 ((1S)-1-benzyl-3-ethylamino-2-hydroxy-3-oxopropyl)carbamic acid 1,1-dimethylethyl ester 
• 209398-28-7 [(S)-1-Benzyl-2-hydroxy-2-(2-hydroxy-ethylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester 
• 222640-00-8 [2-(2-benzenesulfonylamino-ethylcarbamoyl)-1-benzyl-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 
• 316830-80-5 tert-butyl 2(S)-3(RS)-hydroxy-4-oxo-4-(phenylethylamino)-1-phenylbutan-2-ylcarbamate 
• 261919-05-5 N-(Cbz-Leu)-3(S)-amino-2(R,S)-hydroxy-4-phenylbutanoic acid 
• 648433-87-8 2(R)-[3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyryl-amino]-3-phenylpropionic acid methyl ester 
• 648433-96-9 2(S)-[3(S)-(N-tert-butyloxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyrylamino]-3-phenylpropionitrile 
• 648433-92-5 2(R)-[3(S)-(N-tert-butyloxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyrylamino]-3-phenylpropionitrile 
• 209173-80-8 2(RS)-hydroxy-3(S)-amino-4-phenylbutanoic acid 
• 862388-14-5 ((1S)-1-benzyl-2-hydroxy-3-oxo-3-(2,2,2-trifluoroethylamino)propyl)carbamic acid 1,1-dimethylethyl ester 
• 862388-12-3 ((1S)-1-benzyl-3-cyclobutylamino-2-hydroxy-3-oxopropyl)carbamic acid 1,1-dimethylethyl ester 
• 862388-15-6 ((1S)-1-benzyl-3-(2-indanylamino)-2-hydroxy-3-oxopropyl)carbamic acid 1,1-dimethylethyl ester 
• 862388-13-4 ((1S)-1-benzyl-3-butylamino-2-hydroxy-3-oxopropyl)carbamic acid 1,1-dimethylethyl ester 
• 862388-10-1 ((1S)-1-benzyl-3-cyclopropylamino-2-hydroxy-3-oxopropyl)carbamic acid 1,1-dimethylethyl ester 

Relevant academic research and scientific papers

Synthesis of α-Ketoamide-Based Stereoselective Calpain-1 Inhibitors as Neuroprotective Agents

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DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF

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DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION

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Lissencephaly therapeutic agent

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LISSENCEPHALY THERAPEUTIC AGENT

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Synthesis, calpain inhibitory activity, and cytotoxicity of P 2-substituted proline and thiaproline peptidyl aldehydes and peptidyl α-ketoamides

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ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF

The present invention provides a compound represented by the formula (I): (INSERT CHEMICAL FORMULA) (wherein R1 is a lower alkyl substituted by a lower alkoxy or a heterocyclic group, or a heterocyclic group; R2 is a lower alkyl opti

NOVEL THIAZINE OR PYRAZINE DERIVATIVES

An object of the present invention is to synthesize novel compounds having 3-oxo-3, 4-dihydro-2H-1, 4-thiazine or 2-oxo-1, 2, 3, 4-tetrahydropyrazine as a main skeleton. The present invention relates to compounds represented by the following general formula [I] and salts thereof. In the formula, X is S or R6-(A2)n-N, R1 and R2 are H, alkyl, cycloalkyl or aryl, R3 and R4 are H, alkyl, cycloalkyl, aryl or aromatic heterocycles, R5 is H, alkyl, cycloalkyl, aryl or -A3-A4-R7, R6 is H, alkyl, cycloalkyl, OH, alkoxy, aryl, aryloxy or an aromatic heterocycle, R7 is H, alkyl, OH, alkoxy, aryl, aryloxy, amino, alkylamino, arylamino, an aromatic heterocycle or a nonaromatic heterocycle, A1 is alkylene, A2 is carbonyl or sulfonyl, A3 is alkylene, and A4 is carbonyl or oxalyl.