191849-93-1

Usage

Uses

Used in Pharmaceutical Synthesis:
3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be further chemically modified due to the presence of the hydroxy and amino groups.
Used in Drug Development:
In the pharmaceutical industry, 3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid is used as a precursor compound for developing new drugs, leveraging its structural features to target specific biological pathways or receptors.
Used in Chiral Chemistry:
3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid is utilized in chiral chemistry to explore the different properties and potential applications of its R and S enantiomers, which may exhibit distinct biological activities.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid serves as a research tool to investigate the structure-activity relationships of drug candidates and optimize their pharmacological properties.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 209173-80-8 2(RS)-hydroxy-3(S)-amino-4-phenylbutanoic acid 
• 1201292-56-9 (R,S)-α-hydroxy, (S)-β-amino, 4-phenylbutyric acid hydrochloride 
• 72155-45-4 Boc-L-phenylalaninal 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 186393-18-0 ((S)-1-benzyl-2-cyano-2-hydroxy-ethyl)-carbamic acid tert-butyl ester 
• 87694-53-9 Boc-Phe-OH N,O-dimethyl hydroxamate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 3182-95-4 L-Phenylalaninol 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 301544-38-7 tert-butyl ((2S)-4-(tert-butylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)carbamate 

Downstream Products

• 209174-41-4 ((S)-3-tert-Butoxycarbonylamino-2-hydroxy-4-phenyl-butyrylamino)-acetic acid ethyl ester 
• 136138-77-7 {(S)-1-Benzyl-2-[(S)-1-({[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-2-hydroxy-ethyl}-carbamic acid tert-butyl ester 
• 116565-03-8 N-(tert-butyloxycarbonyl)-(2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 116565-10-7 (2R,3S)-N-(tert-butoxycarbonyl)-3-amino-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 820993-44-0 ((1S)-1-benzyl-3-ethylamino-2-hydroxy-3-oxopropyl)carbamic acid 1,1-dimethylethyl ester 
• 209398-28-7 [(S)-1-Benzyl-2-hydroxy-2-(2-hydroxy-ethylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester 
• 247584-46-9 {1-benzyl-2-hydroxy-2-[2-(5-pyridin-2-yl-thiophene-2-sulfonylamino)-ethylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester 
• 222640-00-8 [2-(2-benzenesulfonylamino-ethylcarbamoyl)-1-benzyl-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 
• 316830-80-5 tert-butyl 2(S)-3(RS)-hydroxy-4-oxo-4-(phenylethylamino)-1-phenylbutan-2-ylcarbamate 
• 261919-05-5 N-(Cbz-Leu)-3(S)-amino-2(R,S)-hydroxy-4-phenylbutanoic acid 
• 648433-87-8 2(R)-[3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyryl-amino]-3-phenylpropionic acid methyl ester 
• 648433-96-9 2(S)-[3(S)-(N-tert-butyloxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyrylamino]-3-phenylpropionitrile 
• 648433-92-5 2(R)-[3(S)-(N-tert-butyloxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyrylamino]-3-phenylpropionitrile 
• 209173-80-8 2(RS)-hydroxy-3(S)-amino-4-phenylbutanoic acid 

Relevant academic research and scientific papers

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LISSENCEPHALY THERAPEUTIC AGENT

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ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF

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NOVEL THIAZINE OR PYRAZINE DERIVATIVES

An object of the present invention is to synthesize novel compounds having 3-oxo-3, 4-dihydro-2H-1, 4-thiazine or 2-oxo-1, 2, 3, 4-tetrahydropyrazine as a main skeleton. The present invention relates to compounds represented by the following general formula [I] and salts thereof. In the formula, X is S or R6-(A2)n-N, R1 and R2 are H, alkyl, cycloalkyl or aryl, R3 and R4 are H, alkyl, cycloalkyl, aryl or aromatic heterocycles, R5 is H, alkyl, cycloalkyl, aryl or -A3-A4-R7, R6 is H, alkyl, cycloalkyl, OH, alkoxy, aryl, aryloxy or an aromatic heterocycle, R7 is H, alkyl, OH, alkoxy, aryl, aryloxy, amino, alkylamino, arylamino, an aromatic heterocycle or a nonaromatic heterocycle, A1 is alkylene, A2 is carbonyl or sulfonyl, A3 is alkylene, and A4 is carbonyl or oxalyl.