191862-60-9Relevant academic research and scientific papers
Medium-sized cyclophanes, 62. Synthesis and structure of [2.2]metacyclophane-1,2-diol and conversion into [2.2]metacyclophane-1,2-dione by Swern oxidation
Yamato, Takehiko,Hironaka, Toru,Saisyo, Tatsunori,Manabe, Tomoki,Okuyama, Ken-ichiro
, p. 277 - 288 (2007/10/03)
McMurry cyclization of 1,2-bis(5-t-butyl-2-methyl-3-formylphenyl)ethane 2 afforded anti-[2.2]metacyclophan-1-ene 3 and anti-[2.2]metacyclophane-1,2-diols 4, which were converted into the corresponding 1,2-dione 6 by Swern oxidation.
Synthesis of 1,2,9,10-tetrahydroxy[2.2]metacyclophanes via pinacol coupling reaction of 1,3-benzenedicarboxyaldehydes
Sahade, Daniel A.,Tsukamoto, Ken-Ichi,Thiemann, Thies,Sawada, Tsuyoshi,Mataka, Shuntaro
, p. 2573 - 2580 (2007/10/03)
Tetrahydroxy[2.2]metacyclophanes are formed via the aluminium mediated pinacol coupling reaction of 1,3-benzenedicarboxaldehydes. The results indicate that the presence of functional groups in the aromatic ring of the dialdehydes plays an important role in the formation of the cyclophane structure. Intramolecular coupling reactions as well as a comparison of different reductive systems are discussed in the work.
