192071-32-2

Basic information

• Product Name: 2-diazo-1-(3,4-dimethoxyphenyl)ethanone
• Synonyms: 2-diazo-1-(3,4-dimethoxyphenyl)ethanone
• CAS NO: 192071-32-2
• Molecular Weight: 206.201
• Mol File: 192071-32-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-diazo-1-(3,4-dimethoxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-diazo-1-(3,4-dimethoxyphenyl)ethanone(192071-32-2)
• EPA Substance Registry System: 2-diazo-1-(3,4-dimethoxyphenyl)ethanone(192071-32-2)

Safety Data

• Hazardous Substances Data: 192071-32-2(Hazardous Substances Data)

Upstream product

• 829-20-9 2',4'-dimethoxyacetophenone 
• 60965-26-6 2-Bromo-2',4'-dimethoxyacetophenone 
• 186581-53-3 diazomethane 
• 39828-35-8 2,4-dimethoxybenzoyl chloride 

Downstream Products

• 666175-56-0 (2,4-dimethoxy-phenyl)-acetic acid amide 
• 4783-90-8 2-chloro-1-(2,4-dimethoxyphenyl)ethanone 

Relevant articles and documents

Practical Application of the Aqueous 'Sulfonyl-Azide-Free' (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters

The earlier described 'sulfonyl-Azide-free' ('SAFE') protocol for diazo transfer to CH-Acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a se

Diazoaldehyde Chemistry. Part 1. Transdiazotization of Acylacetaldehydes in Neutral-to-Acidic Medium. A Direct Approach to the Synthesis of α-Diazo-β-oxoaldehydes

First ever non-deformylating transdiazotization of acylacetaldehydes was achieved: the reactions of 2-azido-1-ethylpyridinium tetrafluoroborate (4) with acylacetaldehydes 3 proceeded partially without deformylation to yield 16 new α-diazo-β-oxoaldehydes 1 along with diazomethyl ketones 2, especially in the presence of NaOAc (Scheme 1, Tables 1 and 2).The product distribution was substituent-dependent and could be correlated quantitatively.This new diazotization reaction appears as an alternative, direct, and more general method for the synthesis of these diazooxoaldehydes. α-Oxocycloalkanecarbaldehydes 5 gave only traces (if any) of α-diazocycloalkanones 7, and rearrangement products 6 were isolated (Scheme 2).Mechanisms of the reactions are discussed (Schemes 4 and 5).