192118-47-1Relevant articles and documents
6-Substituted 2-azabicyclo[2.2.1]hept-5-enes by nitrogen-directed radical rearrangement: Synthesis of an epibatidine analogue with high binding affinity at the nicotinic acetylcholine receptor
Hodgson, David M.,Maxwell, Christopher R.,Wisedale, Richard,Matthews, Ian R.,Carpenter, Kate J.,Dickenson, Anthony H.,Wonnacott, Susan
, p. 3150 - 3158 (2007/10/03)
Base-induced isomerisation of epoxide 13 gives an azanortricyclanol 17 which is a precursor for a novel free-radical induced rearrangement to 6-substituted 2-azabicyclo[2.2.1]hept-5-enes 28-31. Compound 31 undergoes selective exo-face hydrogenation to giv