192124-82-6

Basic information

• Product Name: 3,4-Dimethoxy-6-methyl-2-pent-4-enyl-phenol
• Synonyms: 3,4-Dimethoxy-6-methyl-2-pent-4-enyl-phenol
• CAS NO: 192124-82-6
• Molecular Weight: 236.311
• Mol File: 192124-82-6.mol

Chemical Properties

• CAS DataBase Reference: 3,4-Dimethoxy-6-methyl-2-pent-4-enyl-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dimethoxy-6-methyl-2-pent-4-enyl-phenol(192124-82-6)
• EPA Substance Registry System: 3,4-Dimethoxy-6-methyl-2-pent-4-enyl-phenol(192124-82-6)

Safety Data

• Hazardous Substances Data: 192124-82-6(Hazardous Substances Data)

Upstream product

• 192124-38-2 3,4-dimethoxy-6-methylphenoxyltetrahydropyran 
• 72312-07-3 2-hydroxy-4,5-dimethoxytoluene 
• 192123-89-0 3,4-dimethoxy-6-methyl-2-(pent-4-enyl)phenoxytetrahydropyran 

Downstream Products

• 192124-03-1 3,4,4-trimethoxy-6-methyl-2-(pent-4-enyl)cyclohexa-2,5-dienone 

Relevant articles and documents

Intramolecular cationic [5 + 2] cycloaddition reactions promoted by trimethylsilyl triflate in 3.0 M lithium perchlorate-ethyl acetate: Application to a formal total synthesis of (±)-isocomene

Trimethylsilyl triflate is an effective reagent in 3.0 M lithium perchlorate-ethyl acetate for promoting intramolecular cationic [5 + 2] cycloaddition reactions. A formal total synthesis of the angular triquinane isocomene (10) is detailed. Cationic [5 + 2] cycloaddition of quinone monoketal 40 gives rise to tricyclic diketone 35 which is subsequently converted into the known tricyclic ketone 33. Addition of methyl lithium followed by acid-catalyzed rearrangement employing the Pirrung protocol affords (±)-isocomene (10).