19216-97-8Relevant articles and documents
Cyclic Ketones via the Reaction of Dithiols with 1,3-Dichloroacetone. An Unexpected Base-Catalyzed Rearrangement of α,α'-Dithia Ketones
Chiu, Jer-Jye,Grewal, Rupinder S.,Hart, Harold,Ward, Donald L.
, p. 1553 - 1559 (1993)
The reaction of dithiols with 1,3-dichloroacetone under high dilution and catalyzed by cesium carbonate in DMF affords macrocyclic ketones in good yield.Examples of functionalized cyclophanes prepared in this way include 10, 15, 16, 19, 21, and 24.With Na
1,2-DITHIOLANE AND DITHIOL COMPOUNDS USEFUL IN TREATING MUTANT EGFR-MEDIATED DISEASES AND CONDITIONS
-
Paragraph 0334-0335, (2018/08/12)
Compositions of the invention comprise 1,2-dithiolane, dithiol and related compounds useful as therapeutic agents for the treatment and prevention of diseases and conditions associated with aberrant EGFR activity.
SYNTHESIS AND PROPERTIES OF N-SUBSTITUTED 4-AMINO-1,2-DITHIOLANES AND RELATED COMPOUNDS
Povalyaeva, O.S.,Rodionov, V.Ya.,Suvorov, N.M.
, p. 773 - 782 (2007/10/02)
Various methods for the synthesis of 4-acylamino-1,2-dithiolanes through N-substituted 1,3-di(benzylthio)-2-propylamines, which exhibit appreciable nematocidal activity, were studied.The 4-methylamino- and 4-amino-1,2-dithiolanes are extremely unstable.On the basis of a study of the electronic absorption spectra it was suggested that these compounds may undergo polymerization to linear polydisulfides at elevated temperatures.