192185-71-0

Basic information

• Product Name: Tipifarnib (S enantioMer)
• Synonyms: Tipifarnib (S enantioMer);Tipifarnib (IND-58359) S enantiomer;6-[(S)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one;Tipifarnib S
• CAS NO: 192185-71-0
• Molecular Formula: C₂₇H₂₂Cl₂N₄O
• Molecular Weight: 489.39578
• Mol File: 192185-71-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 681.7±55.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• PKA: 7.20±0.10(Predicted)
• CAS DataBase Reference: Tipifarnib (S enantioMer)(CAS DataBase Reference)
• NIST Chemistry Reference: Tipifarnib (S enantioMer)(192185-71-0)
• EPA Substance Registry System: Tipifarnib (S enantioMer)(192185-71-0)

Safety Data

• Hazardous Substances Data: 192185-71-0(Hazardous Substances Data)

Upstream product

• 869217-40-3 (S)-6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1H-quinolin-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 192185-51-6 4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolinone 

Relevant articles and documents

DIASTEREOSELECTIVE SYNTHESIS PROCESS FOR THE PREPARATION OF IMIDAZOLE COMPOUNDS

A diastereoselective synthesis process for the preparation of an enantiomer of 6--[amino(4-chlorophenyl)(1-methyl-1 H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)- 1--methyl-2(1H)-quinolinone which comprises the conversion of (±)-6-[chloro(4--chlomphenyl)(I-m

DIASTEREOSELECTIVE SYNTHESIS PROCESS WITH 6-BROMO-4-(3-CHLOROPHENYL)-2-METHOXY-QUINOLINE

A diastereoselective synthesis process for the preparation of (R)-(+)- 6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(IH)-quinolinone which comprises the preparation of a compound of formula (XVII) : and the stere