192193-69-4Relevant academic research and scientific papers
Studies on chemical modification of monensin. VI. Preparation of C-7 modified monensins via protected 7-oxomonensin and evaluation of their ion transport activity
Nagatsu, Akito,Tabunoki, Yuichiro,Nagai, Shin-Ichi,Ueda, Taisei,Sakakibara, Jinsaku,Hidaka, Hiroyoshi
, p. 966 - 970 (1997)
7-Carboxymethylmonensin (3), 7-aminomonensin (4), and 7-oxomonensin (5) were synthesized via protected 7-oxomonensin (2), which is expected to be a useful intermediate for the preparation of various monensin derivatives. Compounds 3-5 exhibited smaller ion transport activity than monensin (1).
