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2-DIMETHYLAMINO-7-NITROFLUORENE, also known as DMANF, is a synthetic chemical compound that is primarily used in scientific research for its mutagenic and carcinogenic properties. It is commonly used in laboratory settings to study the effects of chemical exposure on DNA and to identify potential carcinogens. DMANF has been found to induce tumors in various animal models, and its potential for causing DNA damage and genetic mutations makes it an important tool for studying the mechanisms of cancer development. Because of its hazardous properties, DMANF should be handled with caution and in accordance with proper safety protocols.

19221-04-6

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19221-04-6 Usage

Uses

Used in Scientific Research:
2-DIMETHYLAMINO-7-NITROFLUORENE is used as a mutagenic and carcinogenic agent for studying the effects of chemical exposure on DNA and identifying potential carcinogens.
Used in Cancer Development Studies:
2-DIMETHYLAMINO-7-NITROFLUORENE is used as a tool for inducing tumors in various animal models and studying the mechanisms of cancer development.
Used in DNA Damage and Genetic Mutation Research:
2-DIMETHYLAMINO-7-NITROFLUORENE is used as a research compound to investigate the potential for causing DNA damage and genetic mutations.
Used in Safety Protocols:
2-DIMETHYLAMINO-7-NITROFLUORENE is used as a reference for developing and implementing proper safety protocols for handling hazardous chemical compounds in laboratory settings.

Check Digit Verification of cas no

The CAS Registry Mumber 19221-04-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,2 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19221-04:
(7*1)+(6*9)+(5*2)+(4*2)+(3*1)+(2*0)+(1*4)=86
86 % 10 = 6
So 19221-04-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H14N2O2/c1-16(2)12-3-5-14-10(8-12)7-11-9-13(17(18)19)4-6-15(11)14/h3-6,8-9H,7H2,1-2H3

19221-04-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-dimethyl-7-nitro-9H-fluoren-2-amine

1.2 Other means of identification

Product number -
Other names N,N-dimethyl-7-nitro-9H-fluoren-2-ylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19221-04-6 SDS

19221-04-6Relevant academic research and scientific papers

Synthesis of Alkylated Aminofluorenes by Palladium-Catalyzed Substitution at Halofluorenes

Saroja, Ginagunta,Pingzhu, Zhang,Ernsting, Nikolaus P.,Liebscher, Juergen

, p. 987 - 990 (2007/10/03)

New N-substituted 2-amino-9,9-dialkylfluorenes optionally bearing electron-withdrawing substituents such as nitro or cyano in position 7 can be synthesized starting from 2-halo-9,9-dialkylfluorenes by Pd-catalyzed substitution with amines. Chiral amino groups can be introduced by this method too. 2-N,N-Dimethylamino-7-nitro-9H-fluorene was obtained in a convenient way by reductive amination. The N-substituted 2-amino-7-nitro-9H-fluorenes are promising candidates for fluorescence probes for femtosecond solvation dynamics.

Progress Towards a Generalized Solvent Polarity Scale: The Solvatochromism of 2-(Dimethylamino)-7-nitrofluorene and Its Homomorph 2-Fluoro-7-nitrofluorene

Catalan, Javier,Lopez, Vicenta,Perez, Pilar,Martin-Villamil, Rosa,Rodriguez, Jose-Gonzalo

, p. 241 - 252 (2007/10/02)

More than 100 solvents and the gas phase were used to develop a solvent dipolarity-polarizability scale that combines the medium dipolarity and polarizability into a single parameter (SPP) calculated from the UV-visible spectra of 2-(dimethylamino)-7-nitrofluorene (DMANF) and its homomorph 2-fluoro-7-nitrofluorene (FNF).The proposed scale compares favourably for nonprotic solvents with existing solvent polarity scales including Kosower's Z, Dimroth and Reichardt's ET(30), Brooker's χR, Dong and Winnick's PY; Kamlet, Abboud, and Taft's ?*, and Drago's S' scale.When data are derived from electronic transitions, they provide an accurate description form the solvent effect in UV-Vis, IR, NMR, and fluorescence spectroscopy as well as in other chemical areas including thermodynamics and kinetics. - Key Words: Polarity scale/ Solvatochromism/ Solvent polarity scale

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