19221-04-6 Usage
General Description
2-DIMETHYLAMINO-7-NITROFLUORENE, also known as DMANF, is a synthetic chemical compound that is primarily used in scientific research for its mutagenic and carcinogenic properties. It is commonly used in laboratory settings to study the effects of chemical exposure on DNA and to identify potential carcinogens. DMANF has been found to induce tumors in various animal models, and its potential for causing DNA damage and genetic mutations makes it an important tool for studying the mechanisms of cancer development. Because of its hazardous properties, DMANF should be handled with caution and in accordance with proper safety protocols.
Check Digit Verification of cas no
The CAS Registry Mumber 19221-04-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,2 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19221-04:
(7*1)+(6*9)+(5*2)+(4*2)+(3*1)+(2*0)+(1*4)=86
86 % 10 = 6
So 19221-04-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H14N2O2/c1-16(2)12-3-5-14-10(8-12)7-11-9-13(17(18)19)4-6-15(11)14/h3-6,8-9H,7H2,1-2H3
19221-04-6Relevant articles and documents
Synthesis of Alkylated Aminofluorenes by Palladium-Catalyzed Substitution at Halofluorenes
Saroja, Ginagunta,Pingzhu, Zhang,Ernsting, Nikolaus P.,Liebscher, Juergen
, p. 987 - 990 (2007/10/03)
New N-substituted 2-amino-9,9-dialkylfluorenes optionally bearing electron-withdrawing substituents such as nitro or cyano in position 7 can be synthesized starting from 2-halo-9,9-dialkylfluorenes by Pd-catalyzed substitution with amines. Chiral amino groups can be introduced by this method too. 2-N,N-Dimethylamino-7-nitro-9H-fluorene was obtained in a convenient way by reductive amination. The N-substituted 2-amino-7-nitro-9H-fluorenes are promising candidates for fluorescence probes for femtosecond solvation dynamics.
