19222-23-2 Usage
Uses
Used in Pharmaceutical Industry:
2,3-dihydro-3-methylidene-1H-isoindol-1-one is used as a key building block for the synthesis of various pharmaceuticals due to its unique structure and reactivity. Its ability to be incorporated into complex molecular frameworks makes it valuable in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3-dihydro-3-methylidene-1H-isoindol-1-one serves as an essential intermediate in the creation of agrochemicals. Its structural attributes allow for the design of compounds with specific pesticidal or herbicidal properties, contributing to more effective crop protection strategies.
Used in Organic Synthesis:
As a versatile intermediate in organic synthesis, 2,3-dihydro-3-methylidene-1H-isoindol-1-one is utilized for the preparation of a wide range of organic compounds. Its distinct imine and isoindole functionalities facilitate various chemical reactions, enabling the synthesis of complex organic molecules for use in different industries, including the production of dyes, polymers, and other specialty chemicals.
Used in Medicinal Chemistry Research:
2,3-dihydro-3-methylidene-1H-isoindol-1-one is employed as a precursor in medicinal chemistry research for the synthesis of bioactive compounds. Its unique structural features make it a promising candidate for the development of new pharmaceutical agents with potential applications in treating various diseases and medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 19222-23-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,2 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 19222-23:
(7*1)+(6*9)+(5*2)+(4*2)+(3*2)+(2*2)+(1*3)=92
92 % 10 = 2
So 19222-23-2 is a valid CAS Registry Number.
19222-23-2Relevant academic research and scientific papers
A Serendipitous One-Pot Cyanation/Hydrolysis/Enamide Formation: Direct Access to 3-Methyleneisoindolin-1-ones
Banik, Trisha,Kaliappan, Krishna P.
, p. 628 - 633 (2020/12/09)
A direct, one-pot conversion of 2’-haloacetophenones to 3-methyleneisoindolin-1-one scaffolds using CuCN as the sole reagent without the need for moisture-free or anaerobic conditions is reported. This serendipitously discovered transformation with a broa
Substituent effect on anionic cycloaromatization of 2-(2-substituted ethynyl)benzonitriles and related molecules
Lu, Wen-Der,Lin, Chi-Fong,Wang, Chyi-Jia,Wang, Shih-Jen,Wu, Ming-Jung
, p. 7315 - 7319 (2007/10/03)
Methanolysis of 2-(2-substituted ethynyl)benzonitriles based on the nature of substituents gave 5-exo product, isoindolones and 6-endo product, isoquinolones, respectively. When a bulky substituent, such as tert-butyl group, was employed in this cyclization reaction, a 5-exo adduct was obtained. Phenyl and thienyl groups which can stabilize the α-anion affect the cyclization reaction to produce the 5-exo adducts. Pyridinyl and pyrazinyl groups can also stabilize the α-anion, but the formation of a more stable intermediate by coordination of sodium with nitrogen atom leads to the 6-endo products.
