192220-01-2Relevant academic research and scientific papers
Synthesis of substituted-δ2-1,2,4-triazolin-5-ones and S-substituted isothiobiureas from 1-aryl/alkyl-6-phenyl-2-thiobiureas
Suni,Nair,Joshua
, p. 1599 - 1605 (2001)
Reaction of 1-aryl/alkyl-6-phenyl-2-thiobiureas 1 with BnCl and BuI in neutral medium at reflux temperature resulted in the formation of the S-alkylated isothiobiureas 2 and 1,2,4-triazolin-5-one derivatives 3. A convenient route to 2 is also reported.
