192322-50-2 Usage
Uses
Used in Pharmaceutical Industry:
CGP 71683 HYDROCHLORIDE is used as a research compound for studying the role of NPY and its receptors in various physiological processes. Its high selectivity for the Y5 receptor makes it a valuable tool in understanding the specific functions and potential therapeutic applications of this receptor.
Used in Cancer Research:
CGP 71683 HYDROCHLORIDE is used as an experimental therapeutic agent for inhibiting the growth and migration of cancer cells, particularly in BT-549 and MDA-MB-231 cell lines. Its ability to target the Y5 receptor may provide insights into the development of novel cancer treatments.
Used in Obesity and Eating Disorder Research:
CGP 71683 HYDROCHLORIDE is used as a research tool to investigate the role of NPY in regulating food intake and body weight. By inhibiting the Y5 receptor, it may help in the development of treatments for obesity and related eating disorders.
Used in Neuroscience Research:
CGP 71683 HYDROCHLORIDE is used as a selective Y5 receptor antagonist to study the involvement of NPY and its receptors in various neurological processes, such as anxiety, depression, and cognitive function. This may contribute to the development of new therapeutic strategies for neurological disorders.
Biological Activity
Extremely selective, non-peptide NPY Y 5 receptor antagonist. Displays > 1000-fold selectivity over Y 1 , Y 2 and Y 4 receptors; IC 50 values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y 5 , Y 1 , Y 2 and Y 4 receptors respectively. Potently inhibits NPY-induced food intake following i.p. administration in diabetic, free-feeding and fasted rats.
Check Digit Verification of cas no
The CAS Registry Mumber 192322-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,3,2 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 192322-50:
(8*1)+(7*9)+(6*2)+(5*3)+(4*2)+(3*2)+(2*5)+(1*0)=122
122 % 10 = 2
So 192322-50-2 is a valid CAS Registry Number.
InChI:InChI=1/C26H29N5O2S.ClH/c27-25-22-9-3-4-10-23(22)30-26(31-25)28-16-18-12-14-19(15-13-18)17-29-34(32,33)24-11-5-7-20-6-1-2-8-21(20)24;/h1-11,18-19,29H,12-17H2,(H3,27,28,30,31);1H/t18-,19-;
