192370-27-7

Upstream product

• 51442-80-9 5-(tetrahydro-2H-pyran-2-yloxy)-2-pentyn-1-ol 
• 192370-25-5 (Z)-5-Hydroxy-3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-pent-3-enoic acid ethyl ester 
• 192370-24-4 (Z)-5-(tert-Butyl-diphenyl-silanyloxy)-3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-pent-3-enoic acid ethyl ester 
• 121353-12-6 tert-Butyl-[(Z)-3-iodo-5-(tetrahydro-pyran-2-yloxy)-pent-2-enyloxy]-diphenyl-silane 
• 121353-11-5 (Z)-3-iodo-5-(tetrahydro-2H-pyran-2-yloxy)pent-2-en-1-ol 
• 192370-26-6 (Z)-5-(3-Benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-pent-3-enoic acid ethyl ester 

Downstream Products

• 192370-28-8 (Z)-3-(2-Azido-ethyl)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-pent-3-enoic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis of the monomeric building blocks of Z-olefinic (PNA) (Z-OPA) containing the bases Adenine and thymine

The synthesis of the Boc-protected Z-olefinic peptide nucleic acid analog (Z-OPA) monomers containing the base thymine II and Cbz-adenine 19 is described, Key step in the synthesis of the underlying carbon framework is a Pd(0)-catalyzed coupling of a viny