192447-61-3Relevant articles and documents
Regioselective synthesis of 2,4,6-triaminopyridines
Shetty, Rupa,Nguyen, Duyan,Flubacher, Dietmar,Ruggle, Franziska,Schumacher, Andreas,Kelly, Martha,Michelotti, Enrique
, p. 113 - 117 (2007/10/03)
A regioselective synthesis of 2,4,6-trisubstituted pyridine is described starting from 2,6-dibromo-4-nitropyridine. All three different regioisomers of the 2,4,6-triamino substituted pyridine have been synthesized in four to five steps. The method described is a general route to unsymmetrical 2,4,6-trisubstituted amino pyridines.
Process for producing pyridinecarboxamides or thiocarboxamides
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, (2008/06/13)
A process for producing N-substituted pyridine carboxamide or thiocarboxamide, comprising reacting a substituted or unsubstituted pyridine metal compound with substituted isocyanate or isothiocyanate to obtain an addition reaction product thereof, and then substituting the metal of said addition reaction product with a proton. The process according to the present invention can be applied even to compounds having an oxidation-susceptible substituent group and, therefore, industrially useful.