192514-51-5Relevant academic research and scientific papers
An efficient synthesis of a key intermediate for vasopressin V2 receptor agonist OPC-51803 by lipase-catalyzed enantioselective transesterification
Ohtani, Tadaaki,Kitano, Kazuyoshi,Matsubara, Jun,Morita, Seiji,Kawano, Yoshikazu,Komatsu, Makoto,Bando, Masahiko,Kido, Masaru,Uchida, Minoru,Tabusa, Fujio
, p. 635 - 643 (2007/10/03)
An efficient and enantioselective synthesis of (R)-[1-(p-toluenesulfonyl)-2,3,4,5 -tetrahydro-1H-1-benzazepin-5-yl]acetic acid (2), a key intermediate in the synthesis of (R)-2-{1-[2-chloro-4-(1-pyrrolidinyl)benzoyl]-2,3,4,5-tetrahydro- 1H-1-benzazepin-5-
Benzazepine derivatives with vasopressin agonistic activity
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, (2008/06/13)
PCT No. PCT/JP96/03652 Sec. 371 Date Jun. 12, 1998 Sec. 102(e) Date Jun. 12, 1998 PCT Filed Dec. 13, 1996 PCT Pub. No. WO97/22591 PCT Pub. Date Jun. 26, 1997Novel benzazepine derivative of the formula [1]: wherein R1 is H or halogen, A is lower alkylene,
