192513-69-2

Upstream product

• 108-05-4 vinyl acetate 
• 192513-68-1 5-hydroxymethyl-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 

Downstream Products

• 192513-75-0 (S)-(+)-5-bromomethyl-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 192513-73-8 (R)-(+)-5-cyanomethyl-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 192514-51-5 (R)-(+)-[1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]acetic acid 

Relevant academic research and scientific papers

An efficient synthesis of a key intermediate for vasopressin V2 receptor agonist OPC-51803 by lipase-catalyzed enantioselective transesterification

An efficient and enantioselective synthesis of (R)-[1-(p-toluenesulfonyl)-2,3,4,5 -tetrahydro-1H-1-benzazepin-5-yl]acetic acid (2), a key intermediate in the synthesis of (R)-2-{1-[2-chloro-4-(1-pyrrolidinyl)benzoyl]-2,3,4,5-tetrahydro- 1H-1-benzazepin-5-

Benzazepine derivatives with vasopressin agonistic activity

PCT No. PCT/JP96/03652 Sec. 371 Date Jun. 12, 1998 Sec. 102(e) Date Jun. 12, 1998 PCT Filed Dec. 13, 1996 PCT Pub. No. WO97/22591 PCT Pub. Date Jun. 26, 1997Novel benzazepine derivative of the formula [1]: wherein R1 is H or halogen, A is lower alkylene,