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(4-AMino-2-Methylphenyl)acetic acid Methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

192650-52-5

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192650-52-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 192650-52-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,6,5 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 192650-52:
(8*1)+(7*9)+(6*2)+(5*6)+(4*5)+(3*0)+(2*5)+(1*2)=145
145 % 10 = 5
So 192650-52-5 is a valid CAS Registry Number.

192650-52-5Relevant academic research and scientific papers

Synthetic method of poly-substituted dimethyl amino phenyl acetic acid compound

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Paragraph 0046-0049; 0060-0063, (2021/03/05)

The invention relates to a synthesis method of a poly-substituted dimethyl amino phenyl acetic acid compound. The synthesis method comprises the following steps: carrying out methyl esterification reaction on a compound shown in a formula I to obtain a co

2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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Page 24, (2010/02/08)

Selected 2-arylacetic acids, their derivatives and pharmaceutical compositions that contain these compounds are useful in inhibiting chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membrane receptors. The compounds are used for the prevention and treatment of pathologies deriving from said activation. In particular, 2(ortho)-substituted arylacetic acids or their derivatives, such as amides and sulfonamides, lack cyclo-oxygenase inhibition activity and are particularly useful in the treatment of neutrophil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion.

Use of EP4 receptor ligands in the treatment of IL-6 involved diseases

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Page 101, (2010/02/06)

Methods of treating IL-6 involved diseases with EP4 receptor ligands, including EP4 receptor antagonists. Assays to determine the effect of test compounds on PGE2-induced whole blood cells activation.

EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS

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, (2008/06/13)

The invention features a method of treating rheumatoid arthritis in a mammal comprising administering an agent that inhibits prostaglandin EP4 receptor (EP4) activity. Also featured is a method of identifying agents that selectively inhibit EP4 activity in vivo.

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