192710-89-7Relevant articles and documents
Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARα
Mizuno, Cassia S.,Ma, Guoyi,Khan, Shabana,Patny, Akshay,Avery, Mitchell A.,Rimando, Agnes M.
, p. 3800 - 3808 (2008/09/21)
Pterostilbene, a naturally occurring analog of resveratrol, has previously shown PPARα activation in H4IIEC3 cells and was found to decrease cholesterol levels in animals. In this study, analogs of pterostilbene were synthesized and their ability to activ
Resveratrol Derivatives and Their Role as Potassium Channels Modulators
Orsini,Verotta,Lecchi,Restano,Curia,Redaelli,Wanke
, p. 421 - 426 (2007/10/03)
A series of stilbenoid analogues of resveratrol (trans-3,4′ ,5-trihydroxystilbene) with a stilbenic or a bibenzylic skeleton have been prepared by partial synthesis from resveratrol and dihydroresveratrol. The synthesized compounds have been evaluated for their ability to modulate voltage-gated channels.
Synthesis of biologically active polyphenolic glycosides (combretastatin and resveratrol series)
Orsini, Fulvia,Pelizzoni, Francesca,Bellini, Barbara,Miglierini, Giuliana
, p. 95 - 109 (2007/10/03)
(E)-3-(β-D-Glucopyranosyloxy)-4',5-dihydroxystilbene (resveratrol 3-β-D-glucoside, piceid), (Z)-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene (combretastatin A-1), (Z)-3'-hydroxy-3,4,4', 5-tetramethoxystilbene (combretastatin A-4), (Z)-2'-hydroxy-3,4,4',5-tetramethoxystilbene (combretastatin iso-A-4), α,β-dihydro-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene (combretastatin B-1), the corresponding glucosides, and related compounds have been synthesized via Wittig reactions followed by,glucosylation under phase-transfer catalysis. Most of the compounds synthesized have been tested with respect to biological activity (cytostatic, cytotoxic, antimitotic, neurotoxic, antiplatelet aggregation activity).