192768-07-3

Upstream product

• 192768-05-1 (1S,2R,3R,4R,4aR,9aR)-6,6,8,8-Tetraisopropyl-1,2,3,4-tetrakis-(2-methoxy-ethoxymethoxy)-hexahydro-5,7,9-trioxa-6,8-disila-benzocycloheptene 
• 142534-59-6 1D-<1,6-(1,1,3,3-tetraisopropyldisiloxanedi-1,3-yl)>-myo-inositol 
• 98-88-4 benzoyl chloride 
• 192768-06-2 (1S,2S,3S,4S,5S,6R)-3,4,5,6-Tetrakis-(2-methoxy-ethoxymethoxy)-cyclohexane-1,2-diol 

Downstream Products

• 192768-04-0 (1R,2S,3S,4R,5R,6S)-2,3,4,5,6-Pentakis-(2-methoxy-ethoxymethoxy)-cyclohexanol 
• 192768-11-9 Octanoic acid (R)-2-{methoxy-[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentakis-(2-methoxy-ethoxymethoxy)-cyclohexyloxy]-phosphorylsulfanyl}-1-octanoyloxymethyl-ethyl ester 

Relevant academic research and scientific papers

Synthesis of enantiomerically pure phosphorothiolate assay substrate for phosphatidylinositol-specific phospholipase C

An optimized synthesis of enantiopure (2R)-1,2-dioctanoyloxy- and (2R)-1,2-dipalmitoyloxypropane-thiophospho-(1D-myo- inositol) is reported starting from R-glycidol and the readily available 1D-1-tert-butyldiphenylsilyl-myo-inositol. The key synthesis of the phosphothiolester bond is carried out by the phosphoramidite chemistry.