192768-33-5

Basic information

• Product Name: 4-[4-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propylamino)-phenoxy]-benzoic acid
• CAS NO: 192768-33-5
• Molecular Weight: 660.834
• Mol File: 192768-33-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[4-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propylamino)-phenoxy]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propylamino)-phenoxy]-benzoic acid(192768-33-5)
• EPA Substance Registry System: 4-[4-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propylamino)-phenoxy]-benzoic acid(192768-33-5)

Safety Data

• Hazardous Substances Data: 192768-33-5(Hazardous Substances Data)

Upstream product

• 21120-78-5 methyl 4-(4-nitrophenoxy)benzoate 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 350-46-9 4-Fluoronitrobenzene 
• 24477-92-7 4-(4-amino-phenoxy)-benzoic acid methyl ester 

Relevant articles and documents

Diarylether inhibitors of farnesyl-protein transferase

The design and synthesis of simple nonpeptide inhibitors of farnesyl-protein transferase (FTase) are described. Cysteine-derived diarylether frameworks are appropriate structural replacements for the C-terminal tetrapeptide portion of the Ras protein, and possess in vitro potency against FTase. Inhibitory activity is dependent on the ring-substitution pattern, and does not require the presence of a C-terminal carboxylate group.