192804-72-1

Basic information

• Product Name: Benzeneacetic acid, 4-(4-hydroxy-1-butynyl)-, methyl ester
• CAS NO: 192804-72-1
• Molecular Formula: C13H14O3
• Molecular Weight: 218.252
• Mol File: 192804-72-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, 4-(4-hydroxy-1-butynyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 4-(4-hydroxy-1-butynyl)-, methyl ester(192804-72-1)
• EPA Substance Registry System: Benzeneacetic acid, 4-(4-hydroxy-1-butynyl)-, methyl ester(192804-72-1)

Safety Data

• Hazardous Substances Data: 192804-72-1(Hazardous Substances Data)

Upstream product

• 63349-52-0 methyl 4-iodophenylacetate 
• 927-74-2 3-Butyn-1-ol 
• 752165-24-5 2-butyn-1-ol 
• 1798-06-7 (4-iodophenyl)acetic acid 

Downstream Products

• 1579295-39-8 methyl 2-(4-(4-phenylpentyl)phenyl)acetate 
• 1579295-38-7 methyl 2-(4-(4-phenylpent-4-enyl)phenyl)acetate 
• 1579295-37-6 methyl 2-(4-(4,4-difluoro-4-phenylbutyl)phenyl)acetate 
• 1579295-36-5 methyl 2-(4-(4-oxo-4-phenylbutyl)phenyl)acetate 
• 1579295-35-4 methyl 2-(4-(4-fluoro-4-phenylbutyl)phenyl)acetate 
• 1579294-37-3 N-hydroxy-2-(4-(4-hydroxy-4-phenylbutyl)phenyl)acetamide 
• 1579295-34-3 methyl 2-(4-(4-hydroxy-4-phenylbutyl)phenyl)acetate 
• 1579295-33-2 methyl 2-(4-(4-oxobutyl)phenyl)acetate 
• 164931-20-8 methyl 4-(4-hydroxy-1-butyl)phenylacetate 
• 164931-25-3 4-[4-(2-methyl-1H-imidazol-1-yl)butyl]phenylacetyl-D-Ser-D-Lys-(2-cyclohexylethyl)amide 
• 1027559-08-5 [(S)-5-[(S)-3-tert-Butoxy-2-(2-{4-[4-(2-isopropyl-imidazol-1-yl)-butyl]-phenyl}-acetylamino)-propionylamino]-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 
• 1026688-12-9 [(S)-5-[(S)-3-tert-Butoxy-2-(2-{4-[4-(2-ethyl-imidazol-1-yl)-butyl]-phenyl}-acetylamino)-propionylamino]-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 
• 1026034-27-4 [(S)-5-[(S)-3-tert-Butoxy-2-(2-{4-[4-(2-iodo-imidazol-1-yl)-butyl]-phenyl}-acetylamino)-propionylamino]-5-(2-cyclohexyl-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents

The present invention relates to compositions and methods to selectively treat fungal infection. More particularly, the invention relates to compounds, compositions thereof, and methods for selectively enhancing fungal sensitivity to antifungal compounds. The compositions of the invention are comprised of a combination of a histone deacetylase inhibitor, or an N-oxide, hydrate, solvate, pharmaceutically acceptable salt, agricultural formulation, prodrug or complex thereof, and an antifungal agent, the histone deacetylase inhibitor being a compound of Formula (I):

COMPOUNDS HAVING β2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY

This invention provides compounds of formula I wherein R1, R2, R3, R4, R5, R6, R7, R8a, R8b, W, a and b are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Accordingly, such compounds are expected to be useful as therapeutic agents for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.

Azabicycloalkane compounds

This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Such compounds are useful for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.