19281-19-7 Usage
Pyrrolidine derivative
A chemical compound derived from pyrrolidine
Pyrrolidine is a heterocyclic compound with a nitrogen atom in the ring. 1-[(3-nitrophenyl)acetyl]pyrrolidine is a derivative of 1-[(3-nitrophenyl)acetyl]pyrrolidine, with a specific functional group attached.
3-nitrophenylacetyl group
A functional group attached to the nitrogen atom of the pyrrolidine ring
This group consists of a phenyl ring with a nitro group (-NO2) at the 3rd position and an acetyl group (-COCH3) attached to it.
Potential applications
Pharmaceutical research
Due to its unique structure and potential biological activity, 1-[(3-nitrophenyl)acetyl]pyrrolidine may be useful in the development of pharmaceutical compounds and drug candidates.
Building block
Synthesis of various pharmaceutical compounds
The compound may serve as a starting material or intermediate in the synthesis of other pharmaceutically relevant molecules.
Nitro group
Confers specific reactivity and properties
The presence of the nitro group (-NO2) in the molecule may provide unique reactivity and properties that can be exploited in medicinal chemistry.
Therapeutic applications
Further research and development
As the compound's potential for therapeutic applications is not yet fully understood, additional research and development may reveal its usefulness in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 19281-19-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,8 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 19281-19:
(7*1)+(6*9)+(5*2)+(4*8)+(3*1)+(2*1)+(1*9)=117
117 % 10 = 7
So 19281-19-7 is a valid CAS Registry Number.
19281-19-7Relevant academic research and scientific papers
Synthesis and biological evaluation of new 4β-anilino-4′-O- demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents
Wang, Li,Yang, Fenyan,Yang, Xiaochun,Guan, Xianghong,Hu, Chunqi,Liu, Tao,He, Qiaojun,Yang, Bo,Hu, Yongzhou
, p. 285 - 296 (2011/03/17)
A series of new 4β-anilino-4′-O-demethyl-4-desoxypodophyllotoxin derivatives were prepared and evaluated for their cytotoxicities against four human cancer cell lines including KB, KB/VCR, A549 and 95D. Most compounds showed better growth-inhibition activities against tested cell lines than that of etoposide (VP-16). Preliminary structure-activity relationships (SARs) were concluded and it indicated that the side chains substituted at 4β position of podophyllotoxin significantly influenced the cytotoxic activity, especially for the drug resistance profile. In vivo studies of compound 26c on highly metastatic human lung cancer xenograft in nude mice showed that it can significantly inhibit tumor growth with administrating by oral route.
Novel Cyclic Urea Derivatives, Preparation Thereof and Pharmaceutical Use Thereof as Kinase Inhibitors
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Page/Page column 49, (2009/04/24)
Compounds of formula (I): wherein Ra, Rb, R, X1 and X2 are as defined in the disclosure, pharmaceutical compositions comprising said compounds, processes for making and methods of using the same are provided.
