19284-92-5Relevant academic research and scientific papers
Highly regioselective para-methylthiolation/bridging methylenation of arylamines promoted by NH4I
Xu, Yinfeng,Cong, Tiantian,Liu, Ping,Sun, Peipei
, p. 9742 - 9745 (2015)
Aryl methyl thioethers and methylene-bridged arylamines were synthesized via highly regioselective para-methylthiolation/bridging methylenation of arylamines using DMSO as the methylthio or methylene source in the presence of NH4I under metal-free conditions. For the substrates with both electron-donating and electron-withdrawing substituents, the reaction proceeded smoothly and gave moderate to good yields.
