192862-13-8Relevant academic research and scientific papers
Preparation process of difluoroacetophenone derivative
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, (2008/06/13)
The invention relates to a process for preparing a difluoroacetophenone derivative (4) by alkylthionating a compound (1) into a compound (2) and reacting this compound with a compound (3). wherein X1is Cl, Br or I, X2and X3/sup
New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moiety
Eto,Kaneko,Takeda,Tokizawa,Sato,Yoshida,Namiki,Ogawa,Maebashi,Ishida,Matsumoto,Asaoka
, p. 173 - 182 (2007/10/03)
New 1,2,4-triazoles (2) having a difluoro(substituted sulfonyl)methyl moiety were designed and synthesized via α,α-difluoro-α-(substituted thio)acetophenones (3). Compounds (2) showed potent antifungal activities against C. albicans, C. krusei, A. flavus
Triazole derivative and pharmaceutical comprising the same as an effective ingredient
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, (2008/06/13)
Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1)
