192864-62-3Relevant articles and documents
Chemistry of the mycalamides: Antiviral and antitumour compounds from a New Zealand marine sponge. Part 6. The synthesis and testing of analogues of the C(7)-C(10) fragment
Abell, Andrew D.,Blunt, John W.,Foulds, Glenn J.,Munro, Murray H. G.
, p. 1647 - 1654 (2007/10/03)
The key structural features associated with the potent cytotoxicity observed in the mycalamide, onnamide, pederin and theopederin series have been defined on the basis of structure-activity studies. A model pharmacophore structure has been proposed and selected examples, with modest bioactivity, synthesized.