35364-99-9

Basic information

• Product Name: (chloromethoxymethyl)benzene
• Synonyms: BUMCl/1-((chloromethoxy)methyl)benzene
• CAS NO: 35364-99-9
• Molecular Formula: C₈H₉ClO
• Molecular Weight: 156.61
• EINECS: 252-527-2
• Mol File: 35364-99-9.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 207.1 ºC at 760 mmHg
• Flash Point: 91.1 ºC
• Appearance: /
• Density: 1.118 g/cm³
• Vapor Pressure: 0.746mmHg at 25°C
• Refractive Index: 1.514
• CAS DataBase Reference: (chloromethoxymethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (chloromethoxymethyl)benzene(35364-99-9)
• EPA Substance Registry System: (chloromethoxymethyl)benzene(35364-99-9)

Safety Data

• Hazardous Substances Data: 35364-99-9(Hazardous Substances Data)

Usage

General Description

"(Chloromethoxymethyl)benzene, also known as Benzyldimethylchlorosilane, is a chemical compound that consists of a benzene ring with a chloromethoxymethyl group attached to it. It is commonly used as a building block in the synthesis of various organic compounds, particularly in the production of pharmaceuticals and agrochemicals. (chloromethoxymethyl)benzene is a versatile reagent in organic chemistry and is often utilized in the formation of carbon-carbon and carbon-heteroatom bonds. It is also used as a reagent in the preparation of silsesquioxanes and in the synthesis of polymers. Additionally, benzyldimethylchlorosilane is known for its ability to facilitate the desilylation of silyl ethers, making it a valuable tool in organic synthesis."

InChI:InChI=1/C8H9ClO/c1-10-8(9)7-5-3-2-4-6-7/h2-6,8H,1H3

Upstream product

• 4885-02-3 Dichloromethyl methyl ether 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 67-56-1 methanol 
• 100-52-7 benzaldehyde 
• 56-23-5 tetrachloromethane 
• 538-86-3 benzyl methyl ether 
• 7782-50-5 chlorine 
• 4460-46-2 3-chloro-3-phenyl-3H-diazirine 
• 19807-41-1 chlorophenylcarbene 
• 7719-09-7 thionyl chloride 
• 75-36-5 acetyl chloride 
• 119072-55-8 tert-butylisonitrile 
• 56377-72-1 (α-Chlor-4-nitrobenzyl)methylether 

Downstream Products

• 74-87-3 methylene chloride 
• 27059-40-1 (1-chlorobutyl)benzene 
• 71375-49-0 2-chloro-4-methoxy-2-methyl-4-phenylbutane 
• 74209-73-7 erythro-2-(methoxyphenylmethyl)-1-cyclohexanone 
• 74209-73-7 threo-2-(methoxyphenylmethyl)-1-cyclohexanone 
• 64610-09-9 1-Chloro-4-(methoxy-phenyl-methanesulfonyl)-benzene 
• 192864-49-6 (1'R,2S)-2-Acetoxy-N-(1'-methoxy-1'-phenylmethyl)-3-phenylpropanamide 
• 192864-50-9 (1'S,2S)-2-Acetoxy-N-(1'-methoxy-1'-phenylmethyl)-3-phenylpropanamide 
• 192864-62-3 (1'R,2R)-2-Acetoxy-N-(1'-methoxy-1'-phenylmethyl)-3-phenylpropanamide 
• 192864-64-5 (1'S,2R)-2-Acetoxy-N-(1'-methoxy-1'-phenylmethyl)-3-phenylpropanamide 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Singlet Halophenylcarbenes as Strong Hydrogen-Bond Acceptors

Chlorophenylcarbene and fluorophenylcarbene were generated in water-doped argon matrices at cryogenic temperatures by photolysis of the corresponding matrix-isolated diazirines. When diffusion of H2O in solid argon was induced by annealing of the matrices at temperatures above 20 K, hydrogen-bonded complexes between the carbenes and water were formed. UV photolysis of these complexes resulted in the formation of benzaldehyde and hydrogen halides HX. The same products were obtained after photolysis of the diazirines in amorphous water ice. Obviously, the primary insertion product of the carbenes into H-OH is unstable under these conditions, and benzaldehyde is formed via secondary photolysis. The stable primary photochemical insertion product of chlorophenylcarbene into an O-H bond was observed in the reaction of the carbene with methanol.

Structures and reactivities of O-methylated Breslow intermediates

As close as you can get: Since Breslow intermediates usually exist in their keto form, their O-protected tautomers may be considered as their closest isolable relatives. A series of these compounds have been synthesized, their structures determined, and the kinetics of their reactions with electrophiles investigated. Copyright

Synthesis of alpha-halo ethers from symmetric acetals and in situ methoxymethylation of an alcohol [1-methoxymethoxy-1-phenylethane]

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