192872-97-2

Upstream product

• 610-81-1 4-hydroxy-2-nitroaniline 
• 106-93-4 ethylene dibromide 

Downstream Products

• 672961-07-8 4-(2-dimethylamino-ethoxy)-2-nitrophenylamine 
• 1018895-55-0 tert-butyl 4-(2-(4-amino-3-nitrophenoxy)ethyl)piperazine-1-carboxylate 
• 1018895-62-9 4-(2-(4-methylpiperazin-1-yl)ethoxy)-2-nitroaniline 
• 193356-91-1 4-Benzyl-1-(2-(1H-benzotriazol-5-oxy)ethyl)piperidine 

Relevant academic research and scientific papers

A far-red emissive two-photon fluorescent probe for quantification of uracil in genomic DNA

We report a new method for dU detection in genomic DNA combined with UNG excision and fluorescent probe labeling. UNG can remove uracil bases to introduce abasic sites, which can react with NRNO to produce intense fluorescence because of the inhibition of

JAK-2 MODULATORS AND METHODS OF USE

This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention