192993-85-4Relevant articles and documents
Construction of the tetracyclic core of (±)-cycloclavine and 4-amino Uhle's ketone
Chen, Jin-Quan,Mi, Yang,Shi, Zi-Fa,Cao, Xiao-Ping
, p. 3801 - 3808 (2018)
A rapid construction of the tetracyclic core (±)-2 of (±)-cycloclavine (1) was accomplished in seven steps and 24% overall yield from commercially available aldehyde 7. Key features include a domino Friedel-Crafts/nitro-Michael reaction to construct the C