193002-33-4

Usage

Uses

Used in Pharmaceutical Industry:
[2-(dimethylamino)-4-pyridinyl]methanol(SALTDATA: HCl) is used as a precursor in the pharmaceutical industry for the synthesis of various medicinal compounds. Its unique chemical structure allows it to serve as a building block for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, [2-(dimethylamino)-4-pyridinyl]methanol(SALTDATA: HCl) is utilized as a valuable reagent in chemical reactions. Its pyridine ring and functional groups enable it to participate in a variety of reactions, contributing to the formation of complex molecular structures.
Used as a Reagent in Chemical Reactions:
The hydrochloride salt form of [2-(dimethylamino)-4-pyridinyl]methanol(SALTDATA: HCl) also finds application as a reagent in chemical reactions. Its improved solubility and stability facilitate its use in various reaction conditions, making it a versatile component in the synthesis of diverse chemical products.

Upstream product

• 100704-10-7 (2-chloropyridin-4-yl)methanol 
• 124-40-3 dimethyl amine 

Relevant academic research and scientific papers

HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME

The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof. The compound has a superior TRPA1 antagonist activity, and can provide a medicament useful for the prophylaxis or treatment of diseases involving TRPA1 antagonist and TRPA1.

Chemical compounds

The invention relates to quinazoline derivatives of the formula: [wherein: Y1represents —O—, —S—, —CH2—, —SO—, —SO2—, —NR5CO—, —CONR6—, —SO2NR7—, —NR8SO2— or —NR9— (wherein R5, R6, R8and R9each independently represents hydrogen, alkyl or alkoxyalkyl); R1represents hydrogen, hydroxy, halogeno, nitro, trifluoromethyl, cyano, alkyl, alkoxy, alkylthio, amino or alkylamino. R2represents hydrogen, hydroxy, halogeno, alkyl, alkoxy, trifluoromethyl, cyano, amino or nitro; m is an integer from 1 to 5; R3represents hydroxy, halogeno, alkyl, alkoxy, alkanoyloxy, trifluoromethyl, cyano, amino or nitro; R4represents a group which is or which contains an optionally substituted pyridone, phenyl or aromatic heterocyclic group] and salts thereof; processes for their preparation and pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.