193085-19-7Relevant academic research and scientific papers
Method for preparing a compound with growth hormone releasing properties
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, (2008/06/13)
A method for preparing a compound of formula I or a salt thereof is disclosed.
Use of growth hormone or a growth hormone secretagogue for promoting bone formation
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, (2008/06/13)
The invention provides a method of enhancing the healing of bone fractures in an animal subjected to distraction osteogenesis, the method comprising administering, to the animal in need thereof, a growth hormone or a growth hormone secretagogue in an amou
Salt forms of (2E)-5-amino-5-methylhex-2-enoic acid N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)amide
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, (2008/06/13)
The compounds disclosed are salts of (2E)-5-amino-5-methylhex-2-enoic acid N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)amide of Formula I which have an aqueous solubility of at least 5 mg/ml, and a
Novel orally active growth hormone secretagogues
Hansen, Thomas K.,Ankersen, Michael,Hansen, Birgit S.,Raun, Kirsten,Nielsen, Karin K.,Lau, Jesper,Peschke, Bernd,Lundt, Behrend F.,Th?gersen, Henning,Johansen, Nils L.,Madsen, Kjeld,Andersen, Peter H.
, p. 3705 - 3714 (2007/10/03)
A novel class of growth hormone-releasing compounds with a molecular weight in the range from 500 to 650 has been discovered. The aim of this study was to obtain growth hormone secretagogues with oral bioavailability. By a rational approach we were able t
