193085-18-6

Upstream product

• 37553-65-4 N-tert-butoxycarbonyl-N-methyl-D-phenylalanine 
• 74-89-5 methylamine 

Downstream Products

• 193085-64-2 [(E)-4-({(R)-2-Biphenyl-4-yl-1-[methyl-((R)-1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-ethyl}-methyl-carbamoyl)-1,1-dimethyl-but-3-enyl]-carbamic acid tert-butyl ester 
• 193085-82-4 [(E)-4-({(R)-2-Benzo[b]thiophen-3-yl-1-[methyl-((R)-1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-ethyl}-methyl-carbamoyl)-1,1-dimethyl-but-3-enyl]-carbamic acid tert-butyl ester 
• 193085-20-0 ((3E)-1,1-Dimethyl-4-(N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)carbamoyl)but-3-enyl)carbamic acid tert-butyl ester 
• 193085-77-7 [(E)-1,1-Dimethyl-4-(methyl-{(R)-1-[methyl-((R)-1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-2-naphthalen-1-yl-ethyl}-carbamoyl)-but-3-enyl]-carbamic acid tert-butyl ester 
• 193085-41-5 [(E)-4-({(R)-2-Benzyloxy-1-[methyl-((R)-1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-ethyl}-methyl-carbamoyl)-1,1-dimethyl-but-3-enyl]-carbamic acid tert-butyl ester 
• 193079-69-5 tabimorelin 
• 193085-62-0 ((1R)-2-(1,1'-biphenyl-4-yl)-1-(methyl-((1R)-1-methylcarbamoyl-2-phenylethyl)carbamoyl)ethyl)methylcarbamic acid tert-butyl ester 
• 193085-19-7 N-Methyl-N-{(1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl}carbamic acid tert-butyl ester 
• 193085-80-2 {(R)-2-Benzo[b]thiophen-3-yl-1-[methyl-((R)-1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-ethyl}-methyl-carbamic acid tert-butyl ester 
• 193085-39-1 N-((1R)-2-Benzyloxy-1-(N-methyl-N-((1R)-1-methylcarbamoyl-2-phenylethyl)carbamoyl)ethyl)N-methylcarbamic acid tert-butyl ester 
• 193085-75-5 methyl-((1R)-1-(methyl-((1R)-1-methylcarbamoyl-2-phenylethyl)carbamoyl)-2-(1-naphthyl)ethyl)carbamic acid tert-butylester 
• 193085-63-1 (2R)-3-(1,1'-biphenyl-4-yl)-N-methyl-2-methylamino-N-((1R)-1-methylcarbamoyl-2-phenylethyl)propionamide 
• 193085-81-3 (2R)-3-(Benzo[b]thiophen-3-yl)-N-methyl-2-methylamino-N-((1R)-1-methylcarbamoyl-2-phenylethyl)propionamide 
• 186840-95-9 (2R)-N-Methyl-2-methylamino-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)-3-(2-naphthyl)propionamide 

Relevant academic research and scientific papers

Method for preparing a compound with growth hormone releasing properties

A method for preparing a compound of formula I or a salt thereof is disclosed.

Use of growth hormone or a growth hormone secretagogue for promoting bone formation

The invention provides a method of enhancing the healing of bone fractures in an animal subjected to distraction osteogenesis, the method comprising administering, to the animal in need thereof, a growth hormone or a growth hormone secretagogue in an amou

Salt forms of (2E)-5-amino-5-methylhex-2-enoic acid N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)amide

The compounds disclosed are salts of (2E)-5-amino-5-methylhex-2-enoic acid N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)amide of Formula I which have an aqueous solubility of at least 5 mg/ml, and a

Compounds with growth hormone releasing properties

Compounds of peptide mimetic nature having the general formula I STR1 wherein a and b are independently 1 or 2, R1 and R2 are independently H or C1-6 alkyl, G and J are independently, inter alia, aromats, and D and E are independently several different groups are growth hormone secretagogous with improved bioavailability.

Novel orally active growth hormone secretagogues

A novel class of growth hormone-releasing compounds with a molecular weight in the range from 500 to 650 has been discovered. The aim of this study was to obtain growth hormone secretagogues with oral bioavailability. By a rational approach we were able t