193085-32-4

Basic information

• Product Name: {2-[(tert-butoxycarbonyl)amino]-2-methylpropoxy}acetic acid
• Synonyms: {2-[(tert-Butoxycarbonyl)amino]-2-methylpropoxy}acetic acid
• CAS NO: 193085-32-4
• Molecular Formula: C₁₁H₂₁NO₅
• Molecular Weight: 247.2881
• Mol File: 193085-32-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 399.881°C at 760 mmHg
• Flash Point: 195.641°C
• Density: 1.106g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.464
• CAS DataBase Reference: {2-[(tert-butoxycarbonyl)amino]-2-methylpropoxy}acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: {2-[(tert-butoxycarbonyl)amino]-2-methylpropoxy}acetic acid(193085-32-4)
• EPA Substance Registry System: {2-[(tert-butoxycarbonyl)amino]-2-methylpropoxy}acetic acid(193085-32-4)

Safety Data

• Hazardous Substances Data: 193085-32-4(Hazardous Substances Data)

Usage

General Description

The chemical "{2-[(tert-butoxycarbonyl)amino]-2-methylpropoxy}acetic acid" is a compound that contains a tert-butoxycarbonyl (Boc) protected amino group, a 2-methylpropoxy side chain, and an acetic acid functional group. The Boc protection group is commonly used in organic synthesis to protect amino groups from unwanted reactions. The 2-methylpropoxy side chain is a hydrophobic group that can affect the compound's solubility and pharmacokinetic properties. The acetic acid functional group is a carboxylic acid that can participate in various chemical reactions. {2-[(tert-butoxycarbonyl)amino]-2-methylpropoxy}acetic acid may have potential applications in medicinal chemistry, organic synthesis, and other fields.

Upstream product

• 127958-62-7 5,5-dimethylmorpholin-3-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 623-73-4 diazoacetic acid ethyl ester 
• 102520-97-8 2-((tert-butyloxycarbonyl)amino)-2-methylpropan-1-ol 
• 249762-00-3 (2-tert-butoxycarbonylamino-2-methyl-propoxy)-acetic acid ethyl ester 

Downstream Products

• 193086-04-3 {1,1-dimethyl-2-[(methyl-{1-[methyl-(1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-2-naphthalen-2-yl-ethyl}-carbamoyl)-methoxy]-ethyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

SUBSTITUTED N-HETEROCYCLIC CARBOXAMIDES AS ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS

The invention provides substituted N-heterocyclic carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat a medical disorder, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.

Compounds with growth hormone releasing properties

Compounds of peptide mimetic nature having the general formula I STR1 wherein a and b are independently 1 or 2, R1 and R2 are independently H or C1-6 alkyl, G and J are independently, inter alia, aromats, and D and E are independently several different groups are growth hormone secretagogous with improved bioavailability.

Synthesis and in vitro characterization of new growth hormone secretagogues derived from ipamorelin with dipeptidomimetic N-terminals

The structural requirements for N-terminal features for the minimal structure of growth hormone secretagogues derived from ipamorelin are investigated. It is found, that incorporation of nonpolar peptidomimetic amino acids at the N-terminal can replace the Aib-His moiety and lead to compounds with high in vitro potency with respect to their growth hormone secretagogue properties. New unnatural amino acids with double bonds, ether- linkages, and 1,3-phenylene-moieties in the backbone proved to be valuable dipeptidomimetics. Using them, growth hormone secretagogues with high potencies were obtained.