193086-06-5

Basic information

• Product Name: Carbamic acid, methyl[(1R)-1-(phenylmethyl)-2-[(phenylmethyl)amino]ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 193086-06-5
• Molecular Formula: C22H30N2O2
• Molecular Weight: 354.492
• Mol File: 193086-06-5.mol

Chemical Properties

• CAS DataBase Reference: Carbamic acid, methyl[(1R)-1-(phenylmethyl)-2-[(phenylmethyl)amino]ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, methyl[(1R)-1-(phenylmethyl)-2-[(phenylmethyl)amino]ethyl]-, 1,1-dimethylethyl ester(193086-06-5)
• EPA Substance Registry System: Carbamic acid, methyl[(1R)-1-(phenylmethyl)-2-[(phenylmethyl)amino]ethyl]-, 1,1-dimethylethyl ester(193086-06-5)

Safety Data

• Hazardous Substances Data: 193086-06-5(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 181646-92-4 (R)-tert-butyl methyl(1-oxo-3-phenylpropan-2-yl)carbamate 
• 181646-55-9 N-((1R)-1-(hydroxymethyl)-2-phenylethyl)-N-methylcarbamic acid tert-butylester 

Downstream Products

• 193086-07-6 N-((1R)-1-aminomethyl-2-phenylethyl)-N-methylcarbamic acid tert-butylester 
• 193086-12-3 (3E)-4-(N-((1R)-1-(N-((1R)-1-benzyl-2-(methylsulfonylamino)ethyl)-N-methylcarbamoyl)-2-(2-naphthyl)ethyl)-N-methylcarbamoyl)-1,1-dimethylbut-3-enylcarbamic acid tert-butyl ester 
• 229176-97-0 {1-[(4-hydroxy-butyrylamino)-methyl]-2-phenyl-ethyl}-methyl-carbamic acid tert-butyl ester 
• 193086-08-7 N-((1R)-1-benzyl-2-((methylsulfonyl)amino)ethyl)-N-methylcarbamic acid tert-butylester 
• 229176-95-8 [1-(acetylamino-methyl)-2-phenyl-ethyl]-methyl-carbamic acid tert-butyl ester 
• 193086-09-8 N-((2R)-2-methylamino-3-phenylpropyl)methansulfonamide 

Relevant articles and documents

New growth hormone secretagogues: C-terminal modified sulfonamide- analogues of NN703

The C-terminal the orally active growth hormone secretagogue NN703 was changed to prepare analogues with inverse sulfonamides and inverse amides. The compounds showed high activity in a in vitro rat pituitary model.

Compounds with growth hormone releasing properties

Compounds of peptide mimetic nature having the general formula I STR1 wherein a and b are independently 1 or 2, R1 and R2 are independently H or C1-6 alkyl, G and J are independently, inter alia, aromats, and D and E are independently several different groups are growth hormone secretagogous with improved bioavailability.