193091-20-2

Upstream product

• 98-88-4 benzoyl chloride 
• 193091-19-9 2,5-anhydro-3,6-thioanhydro-L-mannose ethylene acetal 
• 193091-18-8 2,5-anhydro-4-O-benzoyl-3,6-di-O-methanesulfonyl-L-altrose ethylene acetal 
• 153974-01-7 2,5-anhydro-3,6-di-O-methanesulfonyl-L-idose ethylene acetal 
• 193091-16-6 2,5-anhydro-3,6-di-O-methanesulfonyl-4-O-trifluoromethanesulfonyl-L-idose ethylene acetal 

Downstream Products

• 171036-31-0 Benzoic acid (2S,3R,5R)-5-[1,3]dioxolan-2-yl-2-methyl-tetrahydro-furan-3-yl ester 

Relevant academic research and scientific papers

Stereospecific synthesis of (-)-allo-muscarine from D-glucose: Novel routes to the key chiral synthon

The key chiral synthon in a novel synthesis of (-)-allo-muscarine from D-glucose has been prepared by three independent routes. The most efficient one includes a four-step conversion via the 4-O-benzoyl derivatives of starting 2,5-anhydro-3,5-di-O-methanesulfonyl-L-idose ethylene acetal (2a) into 2,5-anhydro-3,6-dideoxy-L-lyxo-hexose ethylene acetal (4b). The intermediate 4b was efficiently converted into the chiral synthon 2,5-anhydro-4-O-benzoyl-3,6-dideoxy-L-arabino-hexose (4c) by Mitsunobu reaction.