193094-71-2Relevant articles and documents
Synthesis of N-(1-aziridinyl)-6-fluoro-l,4-dihydro-4-oxoquinoline-3-carboxylic acids
Batori, Sandor
, p. 1097 - 1110 (1997)
A series of N-(1-aziridinyl)quinoline-3-carboxylic acid derivatives (e.g. 11a-f, 20a-g, 21a-d) have been synthesized by insertion reaction of nitrenes (e.g. ethyl 7-chloro-6-fluoro-1-nitreno-1,4-dihydro-4-oxoquinoline-3 -carboxylate (9)) into double bond of different olefins (e.g. styrene (10a), see Schemes 2 and 4). The nitrenes were formed in situ by oxidation of N-aminoquinolin-4(1H)-one derivatives (8, 18a,b) using Pb(OAc)4 as oxidizing agent.