19310-95-3

Basic information

• Product Name: 2-Buten-1-ol, 2,3-dimethyl-
• CAS NO: 19310-95-3
• Molecular Formula: C6H12O
• Molecular Weight: 100.161
• Mol File: 19310-95-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Buten-1-ol, 2,3-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Buten-1-ol, 2,3-dimethyl-(19310-95-3)
• EPA Substance Registry System: 2-Buten-1-ol, 2,3-dimethyl-(19310-95-3)

Safety Data

• Hazardous Substances Data: 19310-95-3(Hazardous Substances Data)

Upstream product

• 5072-70-8 1-bromo-2,3-dimethyl-2-butene 
• 563-78-0 2,3-Dimethyl-1-butene 
• 563-79-1 2,3-Dimethyl-2-butene 

Downstream Products

• 360059-48-9 2,2,3-Trimethyl-4,4-diphenyloxetan-3-ylmethanol 
• 360059-41-2 2,3,3-Trimethyl-4,4-diphenyloxetan-2-ylmethanol 
• 18445-02-8 (E)-6,9,10-trimethylundeca-5,9-dien-2-one 
• 687-68-3 5,6-dimethyl-5-hepten-2-one 
• 3899-32-9 (E)-3,6,7-trimethylocta-2,6-dien-1-ol 
• 100609-02-7 2,3-dimethylbut-2-en-1-yl phenylcarbamate 
• 19550-30-2 2,3-dimethylbutanol 
• 190452-73-4 2-(2,3-dimethyl-2-butenyl)phenol 

Relevant articles and documents

Mizoroki–Heck Cyclizations of Amide Derivatives for the Introduction of Quaternary Centers

We report non-decarbonylative Mizoroki–Heck reactions of amide derivatives. The transformation relies on the use of nickel catalysis and proceeds using sterically hindered tri- and tetrasubstituted olefins to give products containing quaternary centers. The resulting polycyclic or spirocyclic products can be obtained in good yields. Moreover, a diastereoselective variant of this method gives access to an adduct bearing vicinal, highly substituted sp3 stereocenters. These results demonstrate that amide derivatives can be used as building blocks for the assembly of complex scaffolds.