3899-32-9Relevant articles and documents
Rerouting and Improving Dauc-8-en-11-ol Synthase from Streptomyces venezuelae to a High Yielding Biocatalyst
Lauterbach, Lukas,Hou, Anwei,Dickschat, Jeroen S.
, p. 7923 - 7929 (2021/04/21)
The dauc-8-en-11-ol synthase from Streptomyces venezuelae was investigated for its catalytic activity towards alternative terpene precursors, specifically designed to enable new cyclisation pathways. Exchange of aromatic amino acid residues at the enzyme surface by site-directed mutagenesis led to a 4-fold increase of the yield in preparative scale incubations, which likely results from an increased enzyme stability instead of improved enzyme kinetics.
Synthesis of teleocidins A, B and their congeners. Part 3. Synthesis of dihydroteleocidin B-4 (dihydroteleocidin B), teleocidin B-3 and teleocidin B-4
Okabe, Kazuaki,Muratake, Hideaki,Natsume, Mitsutaka
, p. 8559 - 8572 (2007/10/02)
Details of the synthesis method of the tumor promoters teleocidin B-3 (3), teleocidin B-4 (4) and dihydroteleocidin B-4 (9) (=dihydroteleocidin B) from (S)- and (R)-methyl N-methyl-N-[7-(3,6,7-trimethyl-1,6-octadien-3-yl)-4-indolyl]-L-valinates (20b and 20a) are presented.
A new synthesis of irones IV (1) 6-substituted geraniols, 6-substituted ionones and tetrahydrofuran analogs
Eschinasi, Emile H.,Cotter, Mary Lou
, p. 3487 - 3494 (2007/10/12)
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