193153-18-3Relevant academic research and scientific papers
From Metal-Organic Framework to Porous Carbon Polyhedron: Toward Highly Reversible Lithium Storage
Peng, Hai-Jun,Hao, Gui-Xia,Chu, Zhao-Hua,Cui, Ying-Lin,Lin, Xiao-Ming,Cai, Yue-Peng
, p. 10007 - 10012 (2017)
By application of a newly designed T-shaped ligand 5-(4-pyridin-4-yl-benzoylamino)isophthalic acid (H2PBAI) to assemble with Zn(II) ions under solvothermal conditions, a novel porous polyhedral metal-organic framework (Zn-PBAI) with pcu topolog
2:2 Complexes from Diphenylpyridiniums and Cucurbit[8]uril: Encapsulation-Promoted Dimerization of Electrostatically Repulsing Pyridiniums
Yang, Bo,Yu, Shang-Bo,Wang, Hui,Zhang, Dan-Wei,Li, Zhan-Ting
, p. 1312 - 1317 (2018)
Rigid linear compounds G1 and G2, which contained two 4-phenylpyridinium (PhPy+) units, have been prepared to investigate their binding with cucurbit[8]uril (CB[8]). X-ray crystallographic structures revealed that in the solid state both compounds were included by CB[8], through antiparallel stacking, to form 2:2 quaternary complexes (G1)2@(CB[8])2 and (G2)2@(CB[8])2. For the former complex, CB[8] entrapped G1 by holding two heterodimers of its Py+ and benzyl units, which were at opposite ends of the backbone. In contrast, for the first time, the second complex disclosed parallel stacking of two cationic Py+ units of G2 in the cavity of CB[8] in the solid state, despite the generation of important electrostatic repulsion. Isothermal titrations in water afforded high apparent association constants of 4.36×106 and 6.43×106 m?1 for 1:1 complexes G1@CB[8] and G2@CB[8], respectively, and 1H NMR spectroscopy experiments in D2O confirmed a similar stacking pattern to that observed in the solid state. A previous study and crystal structures of the 2:1 complexes formed between three new controls, G3–5, and CB[8] did not display such unusual stacking of the cationic Py+ unit; this may be attributed to the multivalency of the two CB[8] encapsulation interactions.
Self-assembled [2]catenane in trapezoidal metallacycles with [Cp?Ir]-corners
Liu, Naifang,Huang, Sheng-Li,Liu, Xiaogang,Luo, He-Kuan,Hor, T. S. Andy
supporting information, p. 12802 - 12805 (2017/12/06)
A series of trapezoidal metallacycles were synthesized by the selective combination of a rigid with a flexible arm. [2]Catenane 3 was obtained by self-assembly when the cavity size of the trapezoidal rings was optimised.
Preparing method of porous metal organic frame with small organic molecule fluorescent recognition function
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, (2017/04/29)
The invention discloses a preparing method of a porous metal organic frame with the small organic molecule fluorescent recognition function. The preparing method includes the following steps that 1, an organic ligand 5-(4-pyridine-4-yl-benzamido)-isophthalic acid (H2PYBI) is synthesized; 2, a Zn-MOF material is synthesized, wherein Zn(NO3)2.6H2O and H2PYBI are weighed, dissolved in solvent, heated in a reaction kettle for reaction and cooled to the room temperature after reaction is finished to obtain the Zn-MOF material; 3, activated complex is prepared, wherein the Zn-MOF material in the heating step 2 to remove guest molecules so as to obtain the activated complex. Compared with the prior art, the porous metal organic frame with the small organic molecule fluorescent recognition function has the structural advantages of high porosity, large specific surface area, regular pore passages and an adjustable skeleton, is high in heat stability and chemical stability and can be directly prepared into a device for detecting nitrobenzene.
Structural modifications of salicylates: Inhibitors of human CD81-receptor HCV-E2 interaction
Holzer, Marcel,Ziegler, Sigrid,Neugebauer, Alexander,Kronenberger, Bernd,Klein, Christian D.,Hartmann, Rolf W.
experimental part, p. 478 - 484 (2009/04/04)
Starting point of the present paper was the result of a virtual screening using the open conformation of the large extracellular loop (LEL) of the CD81-receptor (crystal structure: PDB-ID: 1G8Q). After benzyl salicylate had been experimentally validated to be a moderate inhibitor of the CD81-LEL-HCV-E2 interaction, further optimization was performed and heterocyclic-substituted benzyl salicylate derivatives were synthesized. The compounds were tested for their ability to inhibit the interaction of a fluorescence-labeled antibody to CD81-LEL using HUH7.5 cells. No compound showed an increase concerning the inhibition of the protein-protein interaction compared to benzyl salicylate.
