193206-38-1Relevant articles and documents
Two-ring DNA minor-groove binders consisting of readily available, di-substituted benzene derivatives
Yan, Yinfa,Liu, Min,Gong, Bing
, p. 1469 - 1474 (2007/10/03)
DNA minor-groove binders consisting of two disubstituted benzene rings were prepared. Two ligands showed sequence selectivities higher than some of the best known minor-groove binders containing six-membered rings. Reversing the orientation of amide linkages in one ligand leads to another one with relaxed binding to AT sequences and greatly increased affinity toward GC sequences.