193206-41-6Relevant academic research and scientific papers
Two-ring DNA minor-groove binders consisting of readily available, di-substituted benzene derivatives
Yan, Yinfa,Liu, Min,Gong, Bing
, p. 1469 - 1474 (1997)
DNA minor-groove binders consisting of two disubstituted benzene rings were prepared. Two ligands showed sequence selectivities higher than some of the best known minor-groove binders containing six-membered rings. Reversing the orientation of amide linkages in one ligand leads to another one with relaxed binding to AT sequences and greatly increased affinity toward GC sequences.
Synthetic analogues of netropsin and distamycin. VI. Synthesis of carbocyclic lexitropsins containing a bioreductive element
Markowska,Rozanski
, p. 71 - 76 (2007/10/03)
Carbocyclic derivatives of lexitropsines containing of two aromatic rings, N-dimethylaminopropyl group lonked to carboxyl terminus and 5-[bis(2-chloroethyl)-amino]-2,4-dinitrobenzamide group linked to the amino terminus group were synthesed. The N-termina
