193286-87-2Relevant academic research and scientific papers
Synthesis of 2-(2,6-dichloro-4-pyridyl)-3-propargyl-5-ethyl-6-methyl- 4(3H)-pyrimidinone, a promising new herbicide
Taylor, Edward C.,Zhou, Ping,Tice, Colin M.,Lidert, Zev,Roemmele, Renee C.
, p. 4339 - 4342 (2007/10/03)
A novel synthesis of the promising new herbicide 2-(2,6-dichloro-4-pyridyl)-3-propargyl-5-ethyl-6-methyl-4- (12) is reported which features (I) regioselective carbon, followed by nitrogen, dialkylation of an intermediate dianion, and 2 a tandem 'one-pot' sequence of reactions involving sigmatropic sulfoxide elimination, lithium chloride-induced demethylation of a carbomethoxy grouping, decarboxylation, and isomerization/aromatization.
