193346-77-9

Upstream product

• 193345-25-4 5-amino-3-phenyl-thiazolo[5,4-d]isoxazole 
• 76369-62-5 4-bromo-3-phenylisoxazol-5(4H)-one 
• 78650-97-2 3-phenyl-4(5H)-isoxazolone 
• 17356-08-0 thiourea 
• 193346-71-3 5-bromo-3-phenyl-4(5H)-isoxazolone 

Downstream Products

• 1076-59-1 3-phenyl-4H-isoxazol-5-one 

Relevant academic research and scientific papers

New synthetic methods: Part I - Regioselective 1, 2-transposition of carbonyl group in carbocyclic and heterocyclic ketones

A convenient and simple synthetic method for 1, 2- transposition of keto group in pyrazol-5-ones, indan-1,3-dione and benzofuran-3-one is described.

On the synthesis of fused thiazolo[5,4-d]isoxazoles and a novel rearrangement involving conversion of 5(4H)-isoxazolones to 4(5H)-isoxazolones

The interaction of 4-bromo-3-substituted-(4H)-isoxazol-5-ones (1) with alkyl/aryl thiocarbamides (2), 4-alkyl/aryl thiosemicarbazides (7) and 2, 4-disubstituted thiosemicarbazides (12) afford 5-alkyl/ arylamino-3-substituted-thiazolo [5, 4-d]isoxazoles (3) and 6-amino/anilino-5-alkyl/arylimino-3-substituted-thiazolo[5, 4-d]isoxazoles respectively. An alternate unambiguous one step synthesis is described. The compounds have been characterised by chemical reactions and spectral data.