78650-97-2

Basic information

• Product Name: 4(5H)-Isoxazolone,3-phenyl-(9CI)
• Synonyms: 4(5H)-Isoxazolone,3-phenyl-(9CI)
• CAS NO: 78650-97-2
• Molecular Formula: C₉H₇NO₂
• Molecular Weight: 161.15738
• Product Categories: OXAZOLE
• Mol File: 78650-97-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 248.1±23.0 °C(Predicted)
• Appearance: /
• Density: 1.25±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 4(5H)-Isoxazolone,3-phenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4(5H)-Isoxazolone,3-phenyl-(9CI)(78650-97-2)
• EPA Substance Registry System: 4(5H)-Isoxazolone,3-phenyl-(9CI)(78650-97-2)

Safety Data

• Hazardous Substances Data: 78650-97-2(Hazardous Substances Data)

Upstream product

• 76369-62-5 4-bromo-3-phenylisoxazol-5(4H)-one 
• 193345-25-4 5-amino-3-phenyl-thiazolo[5,4-d]isoxazole 

Downstream Products

• 193346-77-9 5-amino-3-phenyl-thiazolo[4,5-d]isoxazole 
• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 193346-71-3 5-bromo-3-phenyl-4(5H)-isoxazolone 
• 94209-13-9 5-(4-dimethylamino-benzylidene)-3-phenyl-isoxazol-4-one 

Relevant articles and documents

On the synthesis of fused thiazolo[5,4-d]isoxazoles and a novel rearrangement involving conversion of 5(4H)-isoxazolones to 4(5H)-isoxazolones

The interaction of 4-bromo-3-substituted-(4H)-isoxazol-5-ones (1) with alkyl/aryl thiocarbamides (2), 4-alkyl/aryl thiosemicarbazides (7) and 2, 4-disubstituted thiosemicarbazides (12) afford 5-alkyl/ arylamino-3-substituted-thiazolo [5, 4-d]isoxazoles (3) and 6-amino/anilino-5-alkyl/arylimino-3-substituted-thiazolo[5, 4-d]isoxazoles respectively. An alternate unambiguous one step synthesis is described. The compounds have been characterised by chemical reactions and spectral data.