19336-84-6

Usage

Uses

Used as a pH Indicator:
N-(3-Nitro-phenyl)-phthalaMic acid is used as a pH indicator due to its ability to change color in response to different pH levels, making it useful for monitoring and controlling the acidity or alkalinity of solutions.
Used in Pharmaceutical Industry:
N-(3-Nitro-phenyl)-phthalaMic acid is used as an intermediate in the preparation of pharmaceutical products for its reactivity and characteristic properties, contributing to the development of new drugs and medications.
Used as a Reagent in Chemical Synthesis:
In the chemical synthesis industry, N-(3-Nitro-phenyl)-phthalaMic acid is used as a reagent to facilitate various chemical reactions, enabling the production of a wide range of compounds and materials.
Used in Dye and Pigment Production:
N-(3-Nitro-phenyl)-phthalaMic acid is employed in the production of dyes and pigments, where its color and reactivity contribute to the creation of vibrant and stable colorants for various applications, including textiles, plastics, and paints.

InChI:InChI=1/C14H10N2O5/c17-13(11-6-1-2-7-12(11)14(18)19)15-9-4-3-5-10(8-9)16(20)21/h1-8H,(H,15,17)(H,18,19)

Upstream product

• 85-44-9 phthalic anhydride 
• 99-09-2 3-nitro-aniline 
• 88-95-9 Phthaloyl dichloride 
• 36647-25-3 N-(3-nitrophenyl)phthalimide 

Downstream Products

• 36647-25-3 N-(3-nitrophenyl)phthalimide 
• 38228-99-8 N,N'-dibenzylphthalamide 

Relevant academic research and scientific papers

2-(3-Nitrophenylaminocarbonyl)benzoic acid: Hydrogen-bonded sheets of R44(22) rings

In the title compound, C14H10N2O 5, the molecules are linked by a combination of one N - H...O and one O - H...O hydrogen bond into sheets containing a single type of R44(22) ring.

Water mediated, environmentally friendly, step-wise, tandem & one-pot syntheses of 2-(1H-benzo[d]imidazole-2-yl)-N-arylbenzamides

Water mediated and environmentally friendly, step-wise, tandem & one-pot syntheses of 2-(1H-benzo[d]imidazole-2-yl)-N-arylbenzamide derivatives have been developed by simply combining phthalic anhydride, anilines and phenylenediammonium dihydrogenphosphate. This reaction has an easy workup, provides excellent yields, and uses water as the solvent which is considered to be relatively environmentally benign.

The cyclisation of substituted phthalanilic acids in acetic acid solution. A kinetic study of substituted N-phenylphthalimide formation

One novel and ten known substituted 3′- and 4′-phthalanilic acids have been prepared. These have been cyclised to two novel and nine known substituted N-phenylphthalimides by heating with glacial acetic acid. Both phthalanilic acids and imides have been characterised in detail and spectroscopic data are given. The kinetics of cyclisation for phthalanilic acids has been examined in detail, and it has emerged that a complex mechanism is operating. This initially involves a reversible, solvent assisted intramolecular nucleophilic attack by amide nitrogen on the carboxylic acid carbonyl. Clear evidence is seen for a long-lived intermediate as a precursor to imide formation. The observed kinetics are rationalised using a model of rapid pre-equilibration, followed by the slow breakdown of the intermediate to imide. Observed rate constants for pre-equilibration show a well behaved, linear Hammett plot (ρ = -1.1), whereas those for formation of imide do not.

Reaction of cyclic anhydrides with aromatic amines: Part I - Synthesis of anilinic acids from phthalic anhydride

Some unreported anilinic acids 5a-j and 7 have been synthesised and their spectral data reported. Their in vitro insecticidal screening as protectants of maize (Zea mays) against Sitophilus zeamais shows 2-(N-naphthylcarbamoyl)benzoic acid 7 to be the most active member of the series.