19337-60-1

Basic information

• Product Name: 3-Iodcatechol
• Synonyms: 3-Iodcatechol;3-Iodobenzene-1,2-diol;3-iodo-1,2-benzenediol
• CAS NO: 19337-60-1
• Molecular Formula: C₆H₅IO₂
• Molecular Weight: 236.00717
• Mol File: 19337-60-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-Iodcatechol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Iodcatechol(19337-60-1)
• EPA Substance Registry System: 3-Iodcatechol(19337-60-1)

Safety Data

• Hazardous Substances Data: 19337-60-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Iodcatechol is used as a reagent in organic synthesis for its ability to participate in a variety of chemical reactions, facilitating the preparation of different pharmaceutical intermediates. Its presence enhances the reactivity and selectivity of the synthesis processes, making it a valuable component in the production of complex organic molecules.
Used in Pharmaceutical Industry:
3-Iodcatechol is used as a precursor in the development of pharmaceuticals due to its potential as a building block for the synthesis of bioactive compounds. Its unique structure allows for the creation of new drugs with specific therapeutic properties.
Used in Dye and Pigment Production:
3-Iodcatechol is used as a component in the production of dyes and pigments, where its chemical structure contributes to the color and stability of the final products. Its presence in these materials is essential for achieving desired color characteristics and performance in various applications.
Used in Anticancer Drug Development:
3-Iodcatechol is used as a potential candidate for anticancer drug development due to its moderate cytotoxicity toward cancer cells. Its ability to selectively target and affect cancerous cells makes it a promising starting point for the creation of new cancer treatments.
Safety Note:
Due to the potential hazards associated with 3-Iodcatechol, it should be handled with caution and appropriate safety measures should be taken during its use in any application. This includes the use of personal protective equipment and adherence to proper handling and disposal protocols to minimize risks to health and the environment.

Upstream product

• 626-02-8 3-Iodophenol 
• 91-16-7 1,2-dimethoxybenzene 
• 591-50-4 iodobenzene 
• 25245-33-4 1-iodo-2,3-dimethoxybenzene 
• 138769-92-3 cis-(1S,2S)-1,2-dihydroxy-3-iodocyclohexa-3,5-diene 

Downstream Products

• 1010685-17-2 C₃₀H₅₃IO₂ 
• 2411-83-8 methyl-2,3-dihydroxybenzoate 
• 1133-63-7 3-phenylcatechol 
• 67984-81-0 2,3-dihydroxybenzonitrile 
• 113678-91-4 di-hydroxyphenyl-ethylene 
• 1607814-83-4 2-iodo-6-(oxan-2-yloxy)phenol 
• 1607814-73-2 2-iodo-6-(oxan-2-yloxy)phenyl methyl carbonate 
• 1607814-79-8 methyl 2-[2-(methoxymethoxy)phenyl]-8-(oxan-2-yloxy)-4-oxo-4H-chromene-3-carboxylate 
• 1607814-76-5 2-{3-[2-(methoxymethoxy)phenyl]prop-2-ynoyl}-6-(oxan-2-yloxy)phenyl methyl carbonate 
• 1444011-07-7 C₂₀H₁₇IO₂ 
• 1444011-04-4 C₃₄H₃₈O₆ 
• 1444011-10-2 C₅₈H₆₂O₆ 
• 1444011-09-9 C₂₆H₂₉BO₄ 

Relevant articles and documents

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A comparative study of the synthesis of 3-substituted catechols using an enzymatic and a chemoenzymatic method

A series of cis-dihydrodiol metabolites, available from the bacterial dioxygenase-catalysed oxidation of monosubstituted benzene substrates using Pseudomonas putida UV4 , have been converted to the corresponding catechols using both a heterogeneous catalyst (Pd/c) and a naphthalene cis-diol dehydrogenase enzyme present in whole cells of the recombinant strain Escherichia coli DH5α(pUC129: nar B). A comparative study of the merits of both routes to 3-substituted catechols has been carried out and the two methods have been found to be complementary. A similarity in mechanism for catechol formation under both enzymatic and chemoenzymatic conditions, involving regioselective oxidation of the hydroxyl group at C-1, has been found using deuterium labelled toluene cis-dihydrodiols. The potential, of combining a biocatalytic step (dioxygenase-catalysed cis-dihydroxylation) with a chemocatalytic step (Pd/C-catalysed dehydrogenation), into a one-pot route to catechols, from the parent substituted benzene substrates, has been realised.

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