19342-75-7Relevant academic research and scientific papers
Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG)
Shelke, Sachin V.,Gao, Gan-Pan,Mesch, Stefanie,Gaethje, Heiko,Kelm, Soerge,Schwardt, Oliver,Ernst, Beat
, p. 4951 - 4965 (2008/03/14)
The trisaccharide substructure 13 of the ganglioside GQ1bα shows a remarkable affinity for the myelin-associated glycoprotein (MAG). In the search for structurally simplified and pharmacokinetically improved mimics of 13, sialosides with modifications at
Enhanced sialylating activity of O-chloroacetylated 2-thioethyl sialosides
Tsvetkov, Yury E.,Nifantiev, Nikolay E.
, p. 1375 - 1380 (2007/10/03)
It has been shown that O-chloroacetyl protecting groups enhance significantly sialylating activity of 2-thioethyl sialosides in model reactions of α(2-8)-sialylation. Ethyl 4,7,8,9-tetra-O-chloroacetyl-3,5-dideoxy-2- thio-5-trifluoroacetamido-D-glycero-α-
A simple procedure for the synthesis of the methyl and benzyl glycosides of Neu5Ac and 4-epi-Neu5Ac. Conversion of the benzyl and methyl glycosides of Neu5Ac into N-trifluoroacetylneuraminic acid benzyl glycosides
Byramova, Nargiz E.,Tuzikov, Alexander B.,Bovin, Nicolai V.
, p. 161 - 176 (2007/10/02)
From the reaction products of the Kuhn-Bashang synthesis of Neu5Ac, 5-acetamido-3,5-dideoxy-α- and -β-D-glycero-D-talo-2-nonulopyranosonic acid (4-epi-Neu5Ac) were isolated as the acetylated methyl esters (1 and 2).Treatment of methyl (5-acetamido-4,7,8,9
Lipid A and related compounds. XXVI. Syntheses of biologically active penta-O-acetyl-N-glycoloylneuraminyl- and penta-O-acetyl-3-deoxy-D-glycero-D-galacto-2-nonulopyranosonic acid-(α 2 → 6)-D-glucosamine-4-phosphate analogs of lipid A
Ikeda,Kawai,Achiwa
, p. 1305 - 1309 (2007/10/02)
The syntheses of novel penta-O-acetyl-N-glycoloylneuraminyl- and penta-O-acetyl-3-deoxy-n-glycero-D-galacto-2-nonulopyranosonic acid-(α 2 → 6)-D-glucosamine-4-phosphate analogues of lipid A containing sialic acid in place of 3-deoxy-D-manno-2-octulosonic acid are described. Preliminary examination of the biological activity revealed that two synthetic disaccharides showed mitogenic activities and weak antitumor activities.
